Individual level and community level factors affecting exclusive breast feeding among infants under-six months in Ethiopia using multilevel analysis

Background: Exclusive breastfeeding (EBF) is the safest and healthiest option of feeding among infants in the first 6 months throughout the world. Thus, promotion of EBF is essential to prevent complex infant health problems even at the adulthood level. But majority of previous studies focused on individual level determinants of EBF by using basic regression models in localized areas. This study aims to identify individual level and community level determinants of EBF which would be helpful to design appropriate strategies in reducing infant mortality and morbidity. Methods: It is a secondary data analysis using the 2016 Ethiopian Demographic and Health Survey (EDHS) data. A total of 1185 infants under 6 months of age were included in the analysis. Multilevel logistic regression model was employed to investigate factors significantly associated with EBF among under-six month’s infants in Ethiopia. Adjusted odds ratio (AOR) with 95% confidence interval (CI) was used to measure the association of variables whereas Intra cluster correlation (ICC), median odds ratio (MOR), and proportional change in variance (PCV) were used to measure random effects (variation). Result: In multilevel logistic regression; 4–5 months age infant (AOR = 0.04, 95%CI:0.02–0.07), female infants (AOR = 2.51, 95%CI:1.61–3.91), infant comorbidities (AOR = 0.35, 95%CI: 0.21–0.57), household wealth index (AOR = 10.34, 95%CI: 3.14–34.03) and antenatal care (AOR = 2.25, 95%CI:1.32–3.82) were determinants of EBF at individual level. Whereas, contextual region (AOR = 0.30, 95% CI: 0.10–0.87), community level of postnatal visit (AOR = 2.77, 95% CI: 1.26–6.58) and community level of maternal employment (AOR = 2.8, 95% CI: 1.21–6.47) were determinants of EBF at community level. The full model showed up with higher PCV; that is, 46.8% of variation of exclusive breastfeeding was explained by the combined factors at the individual and community levels. Similarly, it showed that the variation in EBF across communities remained statistically significant (ICC = 8.77% and variance = 0.32 with P < 0.001). The MOR at final model indicates there was significant cluster difference for EBF indicating the heterogeneity was explained by both individual and community level factors. Conclusion and recommendation: Our study showed that both individual and community level determinants were significantly associated with EBF practice. Based on our findings it is strongly recommended to promote and enhance antenatal and postnatal care services utilization of mothers and more emphasis should be given for infants with comorbid conditions and those who live in the pastoralist regions. This study was done in Ethiopia, which is located in the North Eastern part of Africa. Contextually, the country is categorized as agrarian, pastoralists and city based population. It has a total of 104,957,000 populations, of which 36,296,657 were women [22]. Majority of the population about, 83.6% living in rural areas and 16.7% of the population reside in urban areas. The average household size in national level is 4.7 persons [14, 23]. The country has fertility rate of 4.6, infant mortality rate (per 1000 live births) of 48, and child mortality rate (per 1000 live births) of 67 [14]. This study used data from the 2016 EDHS (Ethiopia Demographic and health survey) which was conducted from January 18 to June 27, 2016. Thus, a community based cross-sectional study was employed to identify individual level and community level factors affecting EBF among under-six month infants [14]. The source populations for this study were all infants under-six months of age living in Ethiopia and all infants under-six months of age in the selected enumeration areas during the data collection period were the study population. Accordingly, a total of 1185 infants under six months of age which fulfill the eligibility criteria were included in the study using a stratified two stage cluster sampling technique. Where, Enumeration areas (EAs) and households were the primary and secondary sampling units respectively. The detail sampling procedure was published elsewhere [14, 24]. We extracted the outcome and explanatory variables from the EDHS 2016 kids data after getting permission from Measure DHS International Program. A structure and pretested questionnaire was used for data collection during the survey. Comprehensive information about the 2016 EDHS data collection procedure has been found elsewhere [14, 24, 25]. The outcome variable of the study was Exclusive Breastfeeding (EBF) among under-six month infants in Ethiopia. Infant related variables (Age of the infant¸ sex of the infant, birth order, birth weight, birth interval, infant comorbidities, and time of breastfeeding initiation), Maternal socio-demographic variables (Age of the mother, marital status, educational status of mother, occupational status of mother, house hold wealth index, media exposure, number of under-five children, and household family size), and Obstetric and Health care associated variables (ANC utilization, PNC utilization, place of delivery, mode of delivery, delivery assistance, and parity) were individual level predictors of the study. In addition, community level variables included in the study were place of residence, contextual region, community media exposure, community wealth index, community women education, community ANC utilization, community level of employment, and community PNC utilization. The World Health Organization (WHO) defines exclusive breastfeeding (EBF) as when ‘an infant receives only breast milk, no other liquids or solids are given not even water, with the exception of oral rehydration solution, or drops/syrups of vitamins, minerals or medicines’ [4]. It was measured using a 24-h recall among mothers with infants under 6 months of age [4]. In this study, infant comorbidities was generated by aggregating variables (diarrhea, cough, fever, and shortness of breath of infants under six months of age) in the last two weeks preceding the survey, subsequently if at least one of the comorbid was found the response coded as “Yes” otherwise the response coded as “No”. Occupational status of mother was generated by using occupation of the respondent and categorized as currently working (includes all types of work) and currently not working. Community level variables were generated by aggregating the individual characteristics in a cluster since EDHS did not collect data that can directly describe the characteristics of the clusters except place of residence. The aggregates were computed using the proportion of a given variables’ subcategory. Since the aggregate value for all generated variables not normally distributed, it was categorized into groups based on the national median values and based on previous related studies [24, 25]. Community ANC utilization was the proportion of mothers within specific cluster who visited ANC for some number of times. It was categorized using national level quartiles in to low ANC utilized community (when≤25% of women are utilizing ANC), middle (when 25–75% of women are utilizing ANC), and high (when > 75% of women are utilizing ANC) [25]. Community level of PNC utilization was the proportion of women within specific cluster who visit PNC for some number of times. It was categorized as low (when≤50% of women utilized PNC) and high (when> 50% of women utilized PNC) [25]. Community level of media exposure was an aggregate respondent level of exposure for different types of media categorized as “<25% = Low”, “25%-50% = Moderate” and “>50% = high media utilized communities” [25]. Community level of poverty was an aggregate wealth index categorized as “<25% = High”, 25–50% = Moderate” and “>50% = Low poverty communities” [25]. Contextual region Ethiopia is demarcated for administrative purpose into 11 regions, which are classified as agrarian, pastoralist and city based according to the living status of the population. The regions Tigray, Amhara, Oromia, SNNP, Gambella, and Benshangul Gumuz were categorized as agrarian. Somali and Afar regions were grouped to form pastoralist region and Harari region, Addis Ababa and Dire Dawa city administrations were grouped to form city based populations [14, 25]. Community level of women education was the proportion of women in the community who have primary or higher education, which was categorized as low (when≤25% of women were educated), middle (when 25–75% of women were educated) and high ((when > 75% of women were educated) [25]. Community level of employment status was the proportion of women who were employed (had work) in the specific cluster. It was categorized as low (when≤50% of mothers employed) and high (when> 50% of mothers were employed) [24, 25]. Data cleaning was done to check for consistency. Sample weight was used in order to compensate for the unequal probability of selection between the strata that were geographically defined, as well as for non-responses. Weighing of individual interview produces the proper representation of exclusive breastfeeding and related factors. Coding, recoding and exploratory analysis was performed. Categorization was done for continuous variables using information from different literatures and re-categorization was done for categorical variables accordingly. For data analysis STATA version 14.1 was used. Descriptive statistics was used to present frequencies, with percentages in tables and using texts. Four models were considered in the multilevel analysis to determine the model that best fits the data; Model one (Null model) without explanatory variable was developed to evaluate the null hypothesis that there is no cluster level difference in exclusive breast feeding practice that specified only the random intercept and it presented the total variance in exclusive breastfeeding practice among clusters. Model two adjusted for individual variable which assume cluster level difference of exclusive breastfeeding practice is zero. Model three to evaluate community level factors by aggregate cluster difference of exclusive breastfeeding practice. Model four included both adjusted individual and community level factors. The log of the probability of Exclusive breast feeding was modeled using two-level multilevel model as follows [26, 27]: Where, i and j are the level 1 (individual) and level 2 (community) units, respectively; X and Z refer to individual and community-level variables, respectively; πij is the probability of exclusive breastfeeding for the ith infant in the jth community; the β’s is the fixed coefficients. Whereas, β0 is the intercept-the effect on the probability of exclusive breastfeeding use in the absence of influence of predictors and uj showed the random effect (effect of the community on exclusive breastfeeding) for the jth community and eij showed random errors at the individual levels. By assuming each community had different intercept (β0) and fixed coefficient (β), the clustered data nature and the within and between community variations was taken in to account. Multilevel logistic regression analysis was used to analyze the data since it is appropriate for DHS data as it had a hierarchical nature. Multilevel modeling was providing unexplained variation in exclusive breast feeding due to unobserved cluster factors called random effect. All models included a random intercept at the cluster level to capture the heterogeneity among clusters. The measures of association (fixed-effects) estimate the association between likelihood of infants to exclusively breast feeding as the AOR with 95% CI of various explanatory variables were expressed. The crude association between independent variables and dependent variable was done independently and variables having p ≤ 0.2 in Bi-variable analysis were used to select to fit multivariable analysis model. At multivariable analysis variables with p ≤ 0.05 with confidence interval not including the null value (OR = 1) were considered as statistically significant variables with EBF practice. The measures of variation (random-effects) were reported using Intra-cluster correlation (ICC), Median Odds Ratio (MOR) and Proportional Change in Variance (PCV). ICC was used to explain cluster variation while MOR is a measure of unexplained cluster heterogeneity [27]. The ICC shows the variation in exclusive breastfeeding of infants under-six months of age due to community characteristics. The higher the ICC (ICC > 5%), the more relevant was the community characteristics for understanding individual variation in exclusive breastfeeding of infants. The ICC can be calculated as follows: [ICC= δ2uδ2u+δ2e] where δ2u = between group variation, δ2e = with in group variation OR [ICC= δ2δ2+π23], where δ2 is the estimated variance of clusters [26]. The STATA software command can also compute the ICC value of each model. MOR is defined as the median value of the odds ratio between the area at highest likelihood and the area at lowest likelihood of exclusive breastfeeding when randomly picking out two areas and it measures the unexplained cluster heterogeneity; the variation between clusters by comparing two persons from two randomly chosen different clusters. MOR can be calculated using the formula [MOR = exp.(2xδ2+0.6745) ≈ exp(0.95δ)] [26]. In this study MOR shows the extent to which the individual probability of being exclusively breast fed is determined by residential area. The proportional change in variance [PCV= (VA − VB)/VA) *100] where VA = Variance of initial model and VB=Variance of model with more terms measures the total variation attributed by individual level and community level factors in the multilevel model [26]. PCV was computed for each model with respect to the empty model as a reference to show power of the factors in the model explains exclusive breastfeeding practice. Log likelihood test, Deviance Information Criteria (DIC) and Akaike Information Criteria (AIC) were used to estimate the goodness of fit of the adjusted final model in comparison to the preceding models (individual and community level models), the model with the highest value of Log likelihood test and with lowest values of DIC and AIC was considered to be the best fit model. We have checked the presence of multi-collinearity between explanatory variables using standard Error (SE), Variance inflation factor (VIF), variance correlation estimator (VCE) and goodness of fit (gof). VIF < 7.5, VCE < 0.8, gof < 0.05, and SE in the range ± 2 were considered as no multicollinearity among independent variable. All of the results showed that no multicollinearity among independent variables. Ethical clearance was obtained from the Ethical Review Committee of College of Medicine and Health Sciences, Wollo University with approval and supporting letter. Permission to access the data set was obtained from Measure DHS International Program. The data was only used for purpose of this study and not shared to the third party. All data used in this study were anonymous publicly available and aggregated secondary data with not having any personal identity. The data was fully available in the full DHS website (www.measuredhs.com).