Objective Childhood acute malnutrition, in the form of wasting defined by Weight-for-Height Z-Scores, is a major public health concern. It is one of the main reasons for the death of children in developing countries like Ethiopia. Accordingly, this study aimed to assess determinants of wasting among children aged 6-59 months in Meket district, North Wollo zone, North-East Ethiopia. Setting The study was conducted among communities in Meket district, North Wollo zone, North-East Ethiopia. Participants A total of 327 (109 cases and 218 controls) children aged 6-59 months participated in the study. Children from 6 months to 59 months of age who match the definition of case/wasted/ and control/not wasted were eligible for the study. However, children who had physical deformities which make anthropometric measurements inconvenient were excluded from the study. Primary and secondary outcome measures The main outcome measure was wasting. Result The mean ages of the cases and controls were 21.77±11.41 months and 20.13±11.39 months, respectively. Factors that were significantly associated with wasting were: maternal decision making on the use of household money (adjusted odd ratio (AOR)=3.04, 95% CI 1.08 to 7.83), complementary feeding started in a month (AOR=3.02, 95% CI 1.097 to 6.97), food diversity score (AOR=2.64, 95% CI 1.64 to 5.23), frequency of complementary feeding (AOR=6.68, 95% CI 3.6 to 11.25) and history of acute respiratory infections (ARIs) 2 weeks preceding the survey (AOR=3.21, 95% CI 1.07 to 7.86). Conclusion Our result implies that the right time to introduce complementary foods, the frequency of feeding and also the amount of food consumed were some of the crucial factors that needed to be changed in child nutrition to reduce wasting. Furthermore, within the framework of our study, the empowerment of women in the decision-making process and the prevention of ARI should be seen as a necessary benchmark for acute malnutrition.
A community-based case-control study was undertaken to identify determinants of wasting among children aged 6–59 months in Meket district, North Wollo zone, North-East Ethiopia, from January to February 2020. Meket district is located in Amhara regional state and is situated about 670 km north of the capital city of Ethiopia, Addis Ababa. The district is also 245 km away from Bahir Dar and 145 km away from the city of Woldia in North Wollo Zone. It has 2 urban and 32 rural kebeles. Based on Meket district administration reports, the catchment population includes 208 687 people (106 430female and 102 257 male) in 48 532 households. The total number of children aged 6–59 months in this district was 26 879; out of those 13 708 of them were female and 13 171 male.42 There is 1 primary hospital, 13 health centres and 36 health posts in this district. All mothers or caregivers that had children aged 6–59 months and who were present in Meket district kebeles during the study period were the source population. Children aged 6–59 months who were admitted due to wasting (WHZ<−2Z score) with their caregivers or mothers were included in the study as cases. Children aged 6–59 months and attending without wasting who came for integrated community case management, screening, immunisation, growth monitoring promotion, and for other purposes were included as controls. Children who had physical deformities which make anthropometric measurements inconvenient were excluded from the study. For instance, children who were born without hands due to congenital deformities, were wounded or had burnt hands were excluded from the study since they had physical deformities. The sample size was calculated using Epi Info V.7 statistical software, and a case-control study was used. The size of the sample was determined from a previous study that was conducted in North-West Ethiopia, which was similar to our study setting. All candidate variables of wasting were considered and the largest was taken. Accordingly, we took into account children from households of large family size as it was the main associated factor of wasting in the previous study.43 The percentages of exposure among cases and controls in the abovementioned study were 64.4% and 46.6%, respectively. Detecting an OR of 2.7 with 95% CI (Zα/2=1.96), a power of 80% (Zβ=0.84) and a case to control ratio of 1:2 were taken from the previous study. Therefore, the total sample size after adding 5% possible contingency for the non-response rate was 327. Of those, 109 cases and 218 controls were approached. Among the 36 kebeles found in Meket district, 10 were selected using simple random sampling methods. The number of study participants, that is children aged 6–59 months, was assigned for each selected kebele proportionally to its size. The number of children in each kebele was found from the vital statistics report of kebele offices. After establishing the sampling frame, cases were identified and selected during a house-to-house visit in each selected kebele. A simple random sampling technique was used to select households until the sample size was achieved. For more than one wasted child per house, the lottery method was used. Whereas controls were selected after the matching criterion of age was fulfilled according to other inclusion and exclusion criterias. Individual matching was carried out as one case followed by two controls, based on three age categories from the same neighbourhood found through transect walks. Controls were matched to cases accordingly with an age interval similar to that of the cases (±3 months) and based on their place of residence (village or neighbourhood).27 43–47 Wasting is the nutritional deficient state of recent onset related to sudden food deprivation or malabsorption, utilisation of nutrients which results from weight loss, weight-for-height below −2 SD from the WHO median value.48 In this study, acute malnutrition or wasting was used interchangeably which was incorporated in both SAM and MAM. MAM is defined as WHZ between −2 and −3 or MUAC between 115 mm and <125 mm. On the other hand, SAM is defined as WHZ < −3 or MUAC <115 mm, or the presence of bilateral pitting oedema, or both.30 Children aged 6–59 months who were wasted according to the above definition including SAM or MAM. Children who weren’t wasted or did not fulfil the definition of cases. Data were collected from all eligible children by data collectors using an interviewer-administered questionnaire and anthropometric measurements. MUAC was also taken from all children with standardising procedures. In addition to child anthropometry measurement, the mothers or caregivers of the children were interviewed face to face. The mothers or caregivers of the children provided answers on variables such as the socioeconomic and demographic characteristics of the participants. Five nurses and 10 health extension workers for data collection and five supervisors were recruited. The data collectors and supervisors were provided with training for 3 days before the data collection period. The supervisors regularly monitored and supervised the overall activity to ensure the quality of data during the entire data collection period. The questionnaire was adopted from different literatures.27 29 32 34 36 49 50 It was originally prepared in English and then translated to the local language, Amharic. Finally, it was translated back to the English language by a skilled person, who had good proficiency in both English and Amharic, to check its consistency. The questionnaire was also pretested on 5% of actual respondents in Wadla district which is almost similar to the study population of this study. The questionnaire was modified based on the pretest. Moreover, the questionnaire was comprised of different variables including socioeconomic and demographic factors, child medical characteristics, child-caring practices (feeding practice, immunisation), maternal caring characteristics, and environmental health conditions. Household food insecurity was assessed by using the nine standards of the Household Food Insecurity Access Scale Questionnaire.51 We also used the WHO validated 7-item Food Frequency Questionnaire to quantify food diversity score.48 Additionally, the data collectors observed expanded program on immunisation (EPI) cards to check the date of birth of the child and immunisation status. To assess the physical growth and nutritional status of the children, measurements of height and weight were taken. Additionally, their age was determined by interviewing mothers or caregivers or by checking their birthday cards. These anthropometric data were collected using the procedure stipulated by WHO by trained data collectors, measured two times and then the average was taken.51 Anthropometric data were collected through the measurement of the height and weight of children. For those less than 2 years of age, measurement of the height was done without shoes. The height is read to the nearest 0.1 cm by using a horizontal wooden measuring board with the infant in a recumbent position on a hard and flat surface. However, the heights of children 24 months and above were measured using a vertical wooden board by placing the child on the measuring board. In this case, the child was standing upright in the middle of the board. The child’s head, shoulders, buttocks and heels touched the board. The heights (lengths) of the children were recorded to the nearest 0.1 cm. Length is usually greater than standing height by 0.5 cm if the child is 85 cm or more. But, if length cannot be measured standing, 0.5 cm were subtracted from the supine length.51 The weight of the child was measured by one health professional, with a 25 kg hanging sprint, the scale graduated to the nearest 100 gm with minimum clothing and no shoes. Also, the scale should be at eye level to read easily when the child is calm. Calibration was done before weighing each child. This was done by setting it to zero and checking the normality by weighing a material of preknown weight. If there was a difference of 0.01 kg or more between duplicate weighing, or if a measured weight differs by 0.01 kg or more from the known standard, check the scales. Then, adjust or replace them if necessary.51 See online supplemental file 1 for details of tools. bmjopen-2021-057887supp001.pdf Epi Info V.7 and SPSS V.24 were used for data entry and analysis, respectively. Besides, anthropometric data were analysed using the WHO Anthro V.2006 software.52 The outcome variables were dichotomised into cases (1) and controls (0). Then, frequencies and cross-tabulation were used to describe the study population with regard to the relevant variables. Conditional logistic regression was used to fit the data to identify the predictors for wasting. Bivariate logistic regression analysis was conducted to discover the effect of each study variable on the outcome variable. Variables having a value of p<0.2553 on the bivariate analysis entered into a multivariate logistic regression analysis to control the possible confounding. In the multivariate logistic regression analysis, variables with a value of p<0.05 were considered statistically significant. The Hosmer-Lemeshow goodness-of-fit test (χ2/df=4.92; Root Mean Square Error of Approximation (RMSEA)=0.05; Comparative Fit Index (CFI)=0.95; Tucker-Lewis Index (TLI)=0.91) was applied to test the appropriateness of the model. Multicollinearity between independent variables was checked and all of the variables scored variance inflation factors <10. No patient was involved.