Effect of a novel vital sign device on maternal mortality and morbidity in low-resource settings: a pragmatic, stepped-wedge, cluster-randomised controlled trial

Background: In 2015, an estimated 303 000 women died in pregnancy and childbirth. Obstetric haemorrhage, sepsis, and hypertensive disorders of pregnancy account for more than 50% of maternal deaths worldwide. There are effective treatments for these pregnancy complications, but they require early detection by measurement of vital signs and timely administration to save lives. The […]

The cost-effectiveness of using results-based financing to reduce maternal and perinatal mortality in Malawi

Introduction Results-based financing (RBF) is being promoted to increase coverage and quality of maternal and perinatal healthcare in sub-Saharan Africa (SSA) countries. Evidence on the cost-effectiveness of RBF is limited. We assessed the cost-effectiveness within the context of an RBF intervention, including performance-based financing and conditional cash transfers, in rural Malawi. Methods We used a […]

The tipping point of antenatal engagement: A qualitative grounded theory in Tanzania and Zambia

Background: Effective antenatal care is fundamental to the promotion of positive maternal and new-born outcomes. International guidance recommends an initial visit in the first trimester of pregnancy, with a minimum of four antenatal visits in total: the optimum schedule being eight antenatal contacts. In low- and middle-income countries, many women do not access antenatal care […]

Protocol for the PLAY Study: A randomised controlled trial of an intervention to improve infant development by encouraging maternal self-efficacy using behavioural feedback

Introduction The early infant caregiving environment is crucial in the formation of parent-child relationships, neurobehavioural development and thus child outcomes. This protocol describes the Play Love And You (PLAY) Study, a phase 1 trial of an intervention designed to promote infant development through encouraging maternal self-efficacy using behavioural feedback, and supportive interventions. Methods and analysis […]

Signal functions for emergency obstetric care as an intervention for reducing maternal mortality: A survey of public and private health facilities in Lusaka District, Zambia

Background: Zambia’s maternal mortality ratio was estimated at 398/100,000 live births in 2014. Successful aversion of deaths is dependent on availability and usability of signal functions for emergency obstetric and neonatal care. Evidence of availability, usability and quality of signal functions in urban settings in Zambia is minimal as previous research has evaluated their distribution […]

Use of mobile phone consultations during home visits by Community Health Workers for maternal and newborn care: Community experiences from Masindi and Kiryandongo districts, Uganda Global health.

Background: Home visits by Community Health Workers [In Uganda Community Health Workers are given the collective term of Village Health Teams (VHTs). Hereafter referred to as VHTs] is recommended to improve maternal and newborn care. We investigated perceived maternal and newborn benefits of home visits made by VHTs, combined with mobile phone consultations with professional […]

Evolution in caesarean section practices in North Kivu: Impact of caregiver training

Introduction A caesarean section is a major obstetric procedure that can save the life of mother and child. Its purpose is to protect the mother’s health from the complications of childbirth and to protect the baby’s health. In sub-Saharan Africa (SSA), there are major inequalities in access to caesarean sections and significant variations in practices […]

Factors influencing place of delivery for women in Kenya: An analysis of the Kenya demographic and health survey, 2008/2009

Background: Maternal mortality in Kenya increased from 380/100000 live births to 530/100000 live births between 1990 and 2008. Skilled assistance during childbirth is central to reducing maternal mortality yet the proportion of deliveries taking place in health facilities where such assistance can reliably be provided has remained below 50% since the early 1990s. We use […]

Longitudinal patterns of the relation between anxiety, depression and posttraumatic stress disorder among postpartum women with and without maternal morbidities in Northwest Ethiopia: a cross-lagged autoregressive structural equation modelling

Background: The postpartum period is a time where mothers can undergo significant changes that increase vulnerability for depression, anxiety and posttraumatic stress disorder symptoms. However, the direct and indirect factors of depression, anxiety and posttraumatic stress disorder symptoms and their direction of relationships following childbirth is not well investigated in Ethiopia. The aim of this […]

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