Relationships between structure, process and outcome to assess quality of integrated chronic disease management in a rural South African setting: applying a structural equation model

Background: South Africa faces a complex dual burden of chronic communicable and non-communicable diseases (NCDs). In response, the Integrated Chronic Disease Management (ICDM) model was initiated in primary health care (PHC) facilities in 2011 to leverage the HIV/ART programme to scale-up services for NCDs, achieve optimal patient health outcomes and improve the quality of medical […]

The Nkateko health service trial to improve hypertension management in rural South Africa: Study protocol for a randomised controlled trial

Background: South Africa has a high and rising prevalence of hypertension. Many affected individuals are not using medication, and few have controlled blood pressure. Until recently, primary care clinics focused on maternal and child health and management of acute conditions, but new government initiatives have shifted the focus to chronic diseases, including HIV/AIDS and hypertension. […]

Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

Background Non-fatal outcomes of disease and injury increasingly detract from the ability of the world’s population to live in full health, a trend largely attributable to an epidemiological transition in many countries from causes affecting children, to non-communicable diseases (NCDs) more common in adults. For the Global Burden of Diseases, Injuries, and Risk Factors Study […]

Integrated Sustainable childhood Pneumonia and Infectious disease Reduction in Nigeria (INSPIRING) through whole system strengthening in Jigawa, Nigeria: study protocol for a cluster randomised controlled trial

BACKGROUND: Child mortality remains unacceptably high, with Northern Nigeria reporting some of the highest rates globally (e.g. 192/1000 live births in Jigawa State). Coverage of key protect and prevent interventions, such as vaccination and clean cooking fuel use, is low. Additionally, knowledge, care-seeking and health system factors are poor. Therefore, a whole systems approach is […]

The Kusamala Program for primary caregivers of children 6-59 months of age hospitalized with severe acute malnutrition in Malawi: Study protocol for a cluster-randomized controlled trial

Background: Severe acute malnutrition (SAM) is associated with high mortality rates and impairments in growth and development in children that do survive. There are complex nutritional, health, and behavioural risk factors involving severely malnourished children and their primary caregivers, requiring integrated intervention approaches. Methods: A cluster-randomized controlled trial at the Queen Elizabeth Central Hospital in […]

A Prognostic Study for the Development of Risk Prediction Model for the Success of Vaginal Birth Following a Cesarean Surgery at Felege Hiwot Comprehensive Specialized Hospital, Northwest Ethiopia

Background: An attempt at vaginal delivery by a woman who has previously had a cesarean section is known as a trial of labor after cesarean section. The most important issues are how to accurately anticipate successful vaginal birth after cesarean surgery and how to calculate the likelihood of success of vaginal birth after caesarean section […]

Patient satisfaction and perceived quality of care: Evidence from a cross-sectional national exit survey of HIV and non-HIV service users in Zambia

Objective: To examine the associations between perceived quality of care and patient satisfaction among HIV and non-HIV patients in Zambia. Setting: Patient exit survey conducted at 104 primary, secondary and tertiary health clinics across 16 Zambian districts. Participants: 2789 exiting patients. Primary independent variables: Five dimensions of perceived quality of care (health personnel practice and […]

Mortality amongst patients with influenza-associated severe acute respiratory illness, South Africa, 2009-2013

Introduction: Data on the burden and risk groups for influenza-associated mortality from Africa are limited. We aimed to estimate the incidence and risk-factors for in-hospital influenza-associated severe acute respiratory illness (SARI) deaths. Methods: Hospitalised patients with SARI were enrolled prospectively in four provinces of South Africa from 2009- 2013. Using polymerase chain reaction, respiratory samples […]

Tracking immunization coverage, dropout and equity gaps among children ages 12-23 months in Malawi-bottleneck analysis of the Malawi Demographic and Health Survey

Background: Between 2010 and 2016, the proportion of children 12-23 months of age who received full immunization in Malawi decreased from 81% to 76%. Most studies on immunization have mainly focused on the risk factors of vaccination coverage while data on dropouts and equity gaps is very scanty. Thus the aim of the present study […]

Social norms and family planning decisions in South Sudan

Background: With a maternal mortality ratio of 789 per 100,000 live births, and a contraceptive prevalence rate of 4.7%, South Sudan has one of the worst reproductive health situations in the world. Understanding the social norms around sexuality and reproduction, across different ethnic groups, is key to developing and implementing locally appropriate public health responses. […]

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