Characterising infant and young child feeding practices and the consumption of poultry products in rural Tanzania: A mixed methods approach
Suboptimal breastfeeding practices, early initiation of complementary feeding, and monotonous cereal-based diets have been implicated as contributors to continuing high rates of child undernutrition in sub-Saharan Africa. Nutrition-sensitive interventions, including agricultural programs that increase access to nutrient-rich vegetables, legumes, and animal-source foods, have the potential to achieve sustainable improvements in children’s diets. In the quest […]
Assessing delivery practices of mothers over time and over space in Uganda, 2003-2012
Background: It is well known that safe delivery in a health facility reduces the risks of maternal and infant mortality resulting from perinatal complications. What is less understood are the factors associated with safe delivery practices. We investigate factors influencing health facility delivery practices while adjusting for multiple other factors simultaneously, spatial heterogeneity, and trends […]
Household and maternal risk factors for malaria in pregnancy in a highly endemic area of Uganda: A prospective cohort study
Background: Malaria in pregnancy is a major public health challenge, but its risk factors remain poorly understood in some settings. This study assessed the association between household and maternal characteristics and malaria among pregnant women in a high transmission area of Uganda. Methods: A nested prospective study was conducted between 6th September 2016 and 5th […]
Demographics, clinical characteristics and neonatal outcomes in a rural Ugandan NICU
Background: Ninety-six percent of the world’s 3 million neonatal deaths occur in developing countries where the majority of births occur outside of a facility. Community-based approaches to the identification and management of neonatal illness have reduced neonatal mortality over the last decade. To further expand life-saving services, improvements in access to quality facility-based neonatal care […]
Where have all the children gone? High HIV prevalence in infants attending nutrition and inpatient entry points:
Introduction: Despite notable progress towards PMTCT, only 50% of HIV-exposed infants in sub-Saharan Africa were tested within the first 2 months of life and only 30% of HIV-infected infants are on antiretroviral treatment. This study assessed HIV prevalence in infants and children receiving care at various service entry points in primary healthcare facilities in Uganda. […]
Using research to influence sexual and reproductive health practice and implementation in Sub-Saharan Africa: A case-study analysis
Background: Research institutions and donor organizations are giving growing attention to how research evidence is communicated to influence policy. In the area of sexual and reproductive health (SRH) and HIV there is less weight given to understanding how evidence is successfully translated into practice. Policy issues in SRH can be controversial, influenced by political factors […]
Socioeconomic predictors of cognition in Ugandan children: Implications for community interventions
Background: Several interventions to improve cognition in at risk children have been suggested. Identification of key variables predicting cognition is necessary to guide these interventions. This study was conducted to identify these variables in Ugandan children and guide such interventions. Methods: A cohort of 89 healthy children (45 females) aged 5 to 12 years old […]
Postneonatal under-5 mortality in peri-urban and rural Eastern Uganda, 2005-2015
Introduction Community and individual sociodemographic characteristics play an important role in child survival. However, a question remains how urbanisation and demographic changes in sub-Saharan Africa affect community-level determinants for child survival. Methods Longitudinal data from the Iganga/Mayuge Health and Demographic Surveillance Site was used to obtain postneonatal under-5 mortality rates between March 2005 and February […]
Postdischarge mortality in children with acute infectious diseases: Derivation of postdischarge mortality prediction models
Objectives: To derive a model of paediatric postdischarge mortality following acute infectious illness. Design: Prospective cohort study. Setting: 2 hospitals in South-western Uganda. Participants: 1307 children of 6 months to 5 years of age were admitted with a proven or suspected infection. 1242 children were discharged alive and followed up 6 months following discharge. The […]
Hypertension persisting after pre-eclampsia: A prospective cohort study at Mulago Hospital, Uganda
Background: Pre-eclampsia/eclampsia usually resolves after delivery but sometimes hypertension persists and cardiovascular disease develops later. Our objective was to determine the incidence and maternal socio-demographic and obstetric risk factors for persistence of hypertension in women with pre-eclampsia/eclampsia. Methods: This was a prospective cohort study conducted from July 2009 to June 2011 at Mulago Hospital labour […]