Prevalence and determinants of intimate partner violence against mothers of children under-five years in Central Malawi
Background: Intimate partner violence (IPV) against women is a global human rights violation and a public health problem. The phenomenon is linked to adverse health effects for women and children. Mothers of young children in Malawi can be particularly at risk because of gender-based power imbalances. The objectives of this study were to examine the […]
Multiple micronutrient supplementation in Tanzanian infants born to HIV-infected mothers: A randomized, double-blind, placebo-controlled clinical trial
Background: Multiple micronutrients (vitamin B complex and vitamins C and E) were effective at reducing infectious disease morbidity, HIV disease progression, and poor pregnancy outcomes in HIV-infected women. Objective: The objective was to evaluate whether direct supplementation of these micronutrients to HIV-exposed infants reduces mortality and morbidity. Design: Infants born to HIV-infected women from Dar […]
Effects of a community health worker delivered intervention on maternal depressive symptoms in rural Tanzania
Maternal depression affects one in four women in sub-Saharan Africa, yet evidence on effective and scalable interventions is limited. Our objective was to evaluate the effect of a community health worker (CHW) delivered home visit responsive stimulation, health and nutrition intervention, and conditional cash transfers (CCTs) for antenatal care and child growth monitoring attendance on […]
Women empowerment and skilled birth attendance in sub-Saharan Africa: A multicountry analysis
Introduction In 2017, the highest global maternal deaths occurred in sub-Saharan Africa (SSA). The WHO advocates that maternal deaths can be mitigated with the assistance of skilled birth attendants (SBAs) at childbirth. Women empowerment is also acknowledged as an enabling factor to women’s functionality and healthcare utilisation including use of SBAs’ services. Consequently, this study […]
Cost of installing and operating an electronic clinical decision support system for maternal health care: Case of Tanzania rural primary health centres
Background: Poor quality of care is among the causes of high maternal and newborn disease burden in Tanzania. Potential reason for poor quality of care is the existence of a “know-do gap” where by health workers do not perform to the best of their knowledge. An electronic clinical decision support system (CDSS) for maternal health […]
Protocol for the trial to establish a causal linkage between mycotoxin exposure and child stunting: A cluster randomized trial
Background: The number of stunted children has fallen globally but continues to increase in Africa. Stunting is estimated to contribute to 14-17% of child deaths under 5 years of age and is a risk factor for poor cognitive and motor development and educational outcomes. Inadequate dietary intake and disease are thought to be the immediate […]
Gender-based distributional skewness of the United Republic of Tanzania’s health workforce cadres: A cross-sectional health facility survey
Background: While severe shortages, inadequate skills and a geographical imbalance of health personnel have been consistently documented over the years as long term critical challenges in the health sector of the United Republic of Tanzania, there is limited evidence on the gender-based distribution of the health workforce and its likely implications. Extant evidence shows that […]
Biomarkers of systemic inflammation and growth in early infancy are associated with stunting in young Tanzanian children
Stunting can afflict up to one-third of children in resource-constrained countries. We hypothesized that low-grade systemic inflammation (defined as elevations in serum C-reactive protein or alpha-1-acid glycoprotein) in infancy suppresses the growth hormone–insulin-like growth factor (IGF) axis and is associated with subsequent stunting. Blood samples of 590 children from periurban Dar es Salaam, Tanzania, were […]
Seasonal food insecurity in Haydom, Tanzania, Is associated with low birthweight and acute malnutrition: Results from the MAL-ED study
In rural agricultural communities in Africa, particularly those with a single annual harvest, the preharvest period has been associated with increased food insecurity. We estimated the association between seasonal food insecurity and childhood malnutrition in Haydom, Tanzania. Children enrolled in a birth cohort study were followed twice weekly to document food intake and monthly for […]
Did a quality improvement intervention improve quality of maternal health care? Implementation evaluation from a cluster-randomized controlled study
Objective: To test the success of a maternal healthcare quality improvement intervention in actually improving quality. Design: Cluster-randomized controlled study with implementation evaluation; we randomized 12 primary care facilities to receive a quality improvement intervention, while 12 facilities served as controls. Setting: Four districts in rural Tanzania. Participants: Health facilities (24), providers (70 at baseline; […]