Clinical and Genetic Aspects of Huntington’s Disease in the Malian Population
Background: Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder caused by mutation in the HTT gene and characterized by involuntary movements as well as cognitive and behavioral impairment. Since its first description 150 years ago, studies have been reported worldwide. However, genetically confirmed cases have been scarce in Africa. Objective: To describe the clinical […]
comparison between caucasian and West african children for assessing earlier malnutrition
One in two children died of malnutrition in Mali and many are malnourished. The use of mobile technologies could allow these challenges and resolve the difficulties associated with interventions for child survival and maternal health, especially in areas of difficult access, and compensate the inadequacy of infrastructure. In a first step, the purpose of this […]
Factors associated with postpartum hemorrhage maternal death in referral hospitals in Senegal and Mali: A cross-sectional epidemiological survey
Background: Postpartum hemorrhage (PPH) is the leading cause of maternal mortality in Sub-Saharan-Africa (SSA). Although clinical guidelines treating PPH are available, their implementation remains a great challenge in resource poor settings. A better understanding of the factors associated with PPH maternal mortality is critical for preventing risk of hospital-based maternal death. The purpose of this […]
Using routine information system data to assess maternal and perinatal care services in Mali and Senegal (QUARITE trial)
Background: In sub-Saharan Africa, problems of access to relevant and high-quality facility-based statistics hinder the assessment of safe motherhood programs. The objective of this study was to assess the quality of data collected in referral hospitals in Mali and Senegal after the routine information system (RIS) was strengthened. Methods: This was a multicenter observational study […]
Maternal and perinatal health research priorities beyond 2015: An international survey and prioritization exercise
Background: Maternal mortality has declined by nearly half since 1990, but over a quarter million women still die every year of causes related to pregnancy and childbirth. Maternal-health related targets are falling short of the 2015 Millennium Development Goals and a post-2015 Development Agenda is emerging. In connection with this, setting global research priorities for […]
Sexual violence and eclampsia: Analysis of data from demographic and health surveys from seven low-and middle-income countries
Background Scientific literature has provided clear evidence of the profound impact of sexual violence on women’s health, such as somatic disorders and mental adverse outcomes. However, consequences related to obstetric complications are not yet completely clarified. This study aimed to assess the association of lifetime exposure to intimate partner sexual violence with eclampsia. Methods We […]
The dop system of alcohol distribution is dead, but it’s legacy lives on
Objective: Determine the prevalence of Dop, a system of labor payment via alcoholic beverages, in a South African province, and its influence on maternal drinking and fetal alcohol spectrum disorders (FASD). Methods: Data from studies of FASD epidemiology were analyzed. Results: Forty-two percent to 67% of mothers reported drinking. In 1999, 5% of women reported […]
Measles susceptibility in maternal-infant dyads—Bamako, Mali
Measles is endemic in Africa; measles mortality is highest among infants. Infant measles antibody titer at birth is related to maternal immune status. Older mothers are likelier to have had measles infection, which provides higher antibody titers than vaccine-induced immunity. We investigated the relationship between maternal age and measles susceptibility in mother-infant pairs in Mali […]
Mother and newborn survival according to point of entry and type of human resources in a maternal referral system in Kayes (Mali)
Background: Since 2001, a referral system has been operating in Kayes (Mali) to reduce maternal and perinatal deaths. Normal deliveries are managed in community health centers (CHC). Complicated cases are referred to a district health center (DHC) or the regional hospital (RH). Women with obstetric emergencies can directly access the DHC and the RH. Objective. […]
Exclusive breastfeeding rates and associated factors in 13 “economic community of West African states” (ECOWAS) countries
Exclusive breastfeeding (EBF) has important protective effects on child survival and also increases the growth and development of infants. This paper examined EBF rates and associated factors in 13 “Economic Community of West African States” (ECOWAS) countries. A weighted sample of 19,735 infants from the recent Demographic and Health Survey dataset in ECOWAS countries for […]
