The association between plasma choline, growth and neurodevelopment among Malawian children aged 6–15 months enroled in an egg intervention trial
Choline is an essential micronutrient that may influence growth and development; however, few studies have examined postnatal choline status and children’s growth and development in low- and middle-income countries. The aim of this observational analysis was to examine associations of plasma choline with growth and development among Malawian children aged 6–15 months enrolled in an egg […]
Quality of oxytocin and misoprostol in health facilities of Rwanda
Sustainable Development Goal 3.1 calls for a reduction of the maternal mortality ratio to less than 70 per 100,000 live births by 2030. The most important cause of maternal mortality is post-partum haemorrhage (PPH). Oxytocin injections and misoprostol tablets are medicines of first choice for the management of PPH in low- and middle-income countries (LMICs). […]
Out-of-pocket costs and time spent attending antenatal care services: a case study of pregnant women in selected rural communities in Zinder, Niger
Background: Despite an official policy of exemption from health care costs, pregnant women in Niger still face some out-of-pocket costs (OPC) in addition to time costs when they attend antenatal care (ANC) services. We aimed to: 1) assess the OPC for pregnant woman attending ANC, 2) estimate the time spent to attend ANC and the […]
Formative research and development of innovative tools for “better Outcomes in Labour Difficulty” (BOLD): Study protocol Obstetrics
Background: Most complications during labour and childbirth could be averted with timely interventions by skilled healthcare providers. Yet, the quality and outcomes of childbirth care remains suboptimal in many health facilities in low-resource settings. To accelerate the reduction of childbirth-related maternal, fetal and newborn mortality and morbidity, the World Health Organization has initiated the “Better […]
Evaluation of an adaptive, multimodal intervention to reduce postoperative infections following cesarean delivery in Ethiopia: study protocol of the CLEAN-CS cluster-randomized stepped wedge interventional trial
Background: We previously developed and pilot tested Clean Cut, a program to prevent postoperative infections by improving compliance with the WHO Surgical Safety Checklist (SSC) and strengthening adherence to infection control practices. This protocol describes the CheckList Expansion for Antisepsis and iNfection Control in Cesarean Section (CLEAN–CS) trial evaluating our program’s ability to reduce infections […]
A university’s response to people with disabilities in Worcester, Western Cape
Background: The call for institutions of higher education to foster interaction with communities and ensure training is responsive to the needs of communities is well documented. In 2011, Stellenbosch University collaborated with the Worcester community to identify the needs of people with disabilities within the community. How the university was engaging with these identified needs […]
Effect of mobile application user interface improvements on minimum expected home visit coverage by community health workers in Mali: A randomised controlled trial
Background Proactive community case management (ProCCM) has shown promise to advance goals of universa health coverage (UHC). ProCCM community health workers (CHWs) face operational challenges when pursuing their goal of visiting every household in their service area at least twice monthly to proactively find sick patients. We developed a software extension (UHC Mode) to an […]
Use of big data and machine learning methods in the monitoring and evaluation of digital health programs in India: An exploratory protocol
Background: Digital health programs, which encompass the subsectors of health information technology, mobile health, electronic health, telehealth, and telemedicine, have the potential to generate “big data.” Objective: Our aim is to evaluate two digital health programs in India-the maternal mobile messaging service (Kilkari) and the mobile training resource for frontline health workers (Mobile Academy). We […]
Lively Minds: improving health and development through play-a randomised controlled trial evaluation of a comprehensive ECCE programme at scale in Ghana
Introduction Many children in developing countries grow up in environments that lack stimulation, leading to deficiencies in early years of development. Several efficacy trials of early childhood care and education (ECCE) programmes have demonstrated potential to improve child development; evidence on whether these effects can be sustained once programmes are scaled is much more mixed. […]
Verbal autopsy interpretation: A comparative analysis of the InterVA model versus physician review in determining causes of death in the Nairobi DSS
Background: Developing countries generally lack complete vital registration systems that can produce cause of death information for health planning in their populations. As an alternative, verbal autopsy (VA) – the process of interviewing family members or caregivers on the circumstances leading to death – is often used by Demographic Surveillance Systems to generate cause of […]
