Maternal Exposure to Acephate Caused Nephrotoxicity in Adult Offspring Rats Mediated by Excessive Autophagy Activation, Oxidative Stress Induction, and Altered Epithelial Sodium Channel and Na+/K+-ATPase Gene Expression

This study examined how maternal exposure to acephate—an organophosphate-based insecticide—affected the renal development in rat offspring during adulthood. Virgin female Wistar rats were randomly allocated to three groups: group 1 (control) received sterile water; groups 2 and 3 were intragastrically exposed to low (14 mg/kg) and high (28 mg/kg) doses of acephate from day 6 […]

Investigating mediators of the poor pneumonia outcomes of human immunodeficiency virus–exposed but uninfected children

Background. Human immunodeficiency virus–exposed but uninfected (HIV-EU) children have a higher mortality rate than the children of HIV-negative mothers (HIV-unexposed). Causal mediators of the poor health outcomes of HIV-EU children remain poorly defined. Methods. We conducted a hospital-based prospective cohort study of children aged 1 to 23 months with clinically defined pneumonia. The children were […]

Socioeconomic, urban‐rural and sex‐based inequality in infant mortality rate: evidence from 2013 Yemen demographic and health survey

Background: The occurrence of Infant Mortality Rate (IMR) varied globally with most of the cases coming from developing countries including Yemen. The disparity in IMR in Yemen however, has not been well dealt and therefore we examined the IMR inequality based on the most reliable methodology in order to generate evidence-based information for some program […]

Infant feeding practices at routine PMTCT sites, South Africa: Results of a prospective observational study amongst HIV exposed and unexposed infants – birth to 9 months

Background: We sought to investigate infant feeding practices amongst HIV-positive and -negative mothers (0-9 months postpartum) and describe the association between infant feeding practices and HIV-free survival.Methods: Infant feeding data from a prospective observational cohort study conducted at three (of 18) purposively-selected routine South African PMTCT sites, 2002-2003, were analysed. Infant feeding data (previous 4 […]

Child dietary diversity and food (in)security as a potential correlate of child anthropometric indices in the context of urban food system in the cases of north-central Ethiopia

Objective: To investigate the relation of child dietary diversity and household food insecurity along with other socio-demographic with child anthropometric indices in north-central Ethiopia, an area with a high level of food insecurity and inadequate diet quality. Design: A community-based cross-sectional study was used. Settings: The study was conducted in Dessie and Combolcha towns of […]

Effective practices of international volunteering for health: Perspectives from partner organizations

Background: The demand for international volunteer experiences to promote global health and nutrition is increasing and numerous studies have documented the experiences of the international volunteers who travel abroad; however, little is known about effective practices from the perspective of partner organizations. This study aims to understand how variables such as the skill-level of volunteers, […]

Stunting in the Context of Plenty: Unprecedented Magnitudes Among Children of Peasant’s Households in Bukombe, Tanzania

Background: It is perceived that children living in peasants’ households are protected from undernutrition owing to a relative better food availability. However, evidence suggests an increased vulnerability that is not conforming to such norm and varies from one region to another. To address this research gap, we examined the magnitude and factors associated with stunting […]

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