Delays in cancer care for children in low-income and middle-income countries: development of a composite vulnerability index
Background: Early access to diagnosis and care is essential to improve rates of survival from childhood cancer, particularly in low-income and middle-income countries (LMICs). Composite indices are increasingly used to compare country performance in many health fields. We aimed to develop a composite vulnerability index of risk of mortality associated with delays in care for […]
The efficacy of maternal health education and maternal screening on knowledge and the uptake of infant screening for sickle cell disease in Dar-Es-Salaam, Tanzania; a quasi experimental study
Background: Globally, Sickle cell disease (SCD) is one of the most common genetic disease with high childhood mortality. Early identification of babies with SCD through newborn screening (NBS) and linking them to care are among the recommended interventions. The purpose of this study was to assess the efficacy of maternal health education and maternal screening […]
Identifying a Basket of Surgical Procedures to Standardize Global Surgical Metrics: An International Delphi Study
Objective:We aimed to define a globally applicable list of surgical procedures, or “basket,”which could represent a health system’s capacity to provide surgical care and standardize global surgical measurement.Summary of Background Data:Six indicators have been proposed to assess access to safe, affordable, timely surgical and anesthesia care, with a focus on laparotomy, cesarean section, and treatment […]
Multisite, mixed methods study to validate 10 maternal health system and policy indicators in Argentina, Ghana and India: A research protocol
Introduction Most efforts to assess maternal health indicator validity focus on measures of service coverage. Fewer measures focus on the upstream enabling environment, and such measures are typically not research validated. Thus, methods for validating system and policy-level indicators are not well described. This protocol describes original multicountry research to be conducted in Argentina, Ghana […]
Clinical and Genetic Aspects of Huntington’s Disease in the Malian Population
Background: Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder caused by mutation in the HTT gene and characterized by involuntary movements as well as cognitive and behavioral impairment. Since its first description 150 years ago, studies have been reported worldwide. However, genetically confirmed cases have been scarce in Africa. Objective: To describe the clinical […]
Optimal Configuration of Hybrid Energy System for Rural Electrification of Community Healthcare Facilities
The unavailability of a constant power supply has been a major problem in remote communities in Africa as it impedes the proper operation of healthcare facilities in these locations. This has deprived inhabitants of free access to good healthcare services, thereby resulting in an increase in maternal and child mortality rates in rural communities in […]
Women’s preferences for maternal healthcare services in bangladesh: Evidence from a discrete choice experiment
Despite substantial improvements in several maternal health indicators, childbearing and birthing remain a dangerous experience for many women in Bangladesh. This study assessed the relative importance of maternal healthcare service characteristics to Bangladeshi women when choosing a health facility to deliver their babies. The study used a mixed-methods approach. Qualitative methods (expert interviews, focus group […]
Reduced transplacental transfer of antimalarial antibodies in Kenyan HIV-exposed uninfected infants
Background. Altered neonatal immune responses may contribute to the increased morbidity observed in HIV-exposed but uninfected (HEU) infants compared with HIV-unexposed uninfected (HUU) infants. We sought to examine the effects of prenatal HIV and malaria exposure on maternal and neonatal plasma cytokine profiles and transplacental antibody transfer. Methods. Forty-nine HIV+ and 50 HIV- women and […]
eRegistries: Governance for electronic maternal and child health registries
Background: The limited availability of maternal and child health data has limited progress in reducing mortality and morbidity among pregnant women and children. Global health agencies, leaders, and funders are prioritizing strategies that focus on acquiring high quality health data. Electronic maternal and child health registries (eRegistries) offer a systematic data collection and management approach […]
The triple threat of pregnancy, HIV infection and malaria: Reported causes of maternal mortality in two nationwide health facility assessments in Mozambique, 2007 and 2012
Background: The paper’s primary purpose is to determine changes in magnitude and causes of institutional maternal mortality in Mozambique. We also describe shifts in the location of institutional deaths and changes in availability of prevention and treatment measures for malaria and HIV infection. Methods: Two national cross-sectional assessments of health facilities with childbirth services were […]
