Effect of the introduction of pneumococcal conjugate vaccination on invasive pneumococcal disease in The Gambia: a population-based surveillance study

Background Little information is available about the effect of pneumococcal conjugate vaccines (PCVs) in low-income countries. We measured the effect of these vaccines on invasive pneumococcal disease in The Gambia where the 7-valent vaccine (PCV7) was introduced in August, 2009, followed by the 13-valent vaccine (PCV13) in May, 2011. Methods We conducted population-based surveillance for […]

How do diverse low-income and middle-income countries implement primary healthcare team integration to support the delivery of comprehensive primary health care? A mixed-methods study protocol from India, Mexico and Uganda

Introduction Attainment of universal health coverage is feasible via strengthened primary health systems that are comprehensive, accessible, people-centred, continuous and coordinated. Having an adequately trained, motivated and equipped primary healthcare workforce is central to the provision of comprehensive primary healthcare (CPHC). This study aims to understand PHC team integration, composition and organisation in the delivery […]

The use of a speaking book® to enhance vaccine knowledge among caregivers in the Gambia: A study using qualitative and quantitative methods

Objectives To measure the usefulness of a Speaking Book (SB) as an educational tool for enhancing knowledge, understanding and recall of key vaccine-related information among caregivers in The Gambia, as well as its acceptability and relevance as a health promotion tool for caregivers and healthcare workers. Design and setting We developed a multimedia educational tool, […]

Multitype violence exposures and adolescent antiretroviral nonadherence in South Africa

Objectives: HIV-positive adolescents have low-ART adherence, with consequent increased risks of mortality, morbidity, and viral resistance. Despite high rates of violence against children in the Africa region, no known studies have tested impacts on HIV-positive adolescents. We examine associations of ART adherence with adolescent violence victimization by caregivers, teachers, peers, community members, and healthcare providers. […]

“… I would have left that man long time ago but, …” exploring circumstances of and motivators for repeat adolescent birth in Eastern Uganda

Background: First birth before 18 years has declined in Uganda unlike repeat adolescent birth (=second or more births before age 20 years). We explored the circumstances of and motivators for repeat adolescent birth in Eastern Uganda. Methods: Between January and March 2020, we conducted a qualitative study involving 70 individual in-depth interviews with purposively selected […]

Dietary diversity and nutritional status of preschool children in north west province, south africa: A cross sectional study

Preschool children consume diets inadequate to meet their macro and micronutrient requirements, which ultimately affect their nutritional status due to lack of dietary diversity. A cross sectional study was conducted to investigate the association between dietary diversity scores (DDS) and the nutritional status of 379 preschool children in North West Province of South Africa. A […]

An instrumental variable probit modeling of covid-19 vaccination compliance in Malawi

COVID-19 remains a pressing development concern in Malawi. The third wave of viral infection upsurge raised significant concerns on people’s compliance with preventive methods already introduced by the government, among which vaccination is notable. This study analysed the factors influencing COVID-19 vaccination compliance in Malawi. The data were the ninth round of the telephone-based survey […]

Understanding patterns of family support and its role on viral load suppression among youth living with HIV aged 15 to 24 years in southwestern Uganda

Background: Active family support helps as a buffer against adverse life events associated with antiretroviral therapy (ART) uptake and adherence. There is limited data available to explain how family support shapes and affects individual healthcare choices, decisions, experiences, and health outcomes among youth living with HIV (YLWH). We aimed to describe family support patterns and […]

Mothers’ dietary practices in the amoron’i mania region Madagascar

Introduction: Madagascar has one of the highest prevalence’s of malnutrition worldwide. Dietary practice is an important element to consider in the fight against malnutrition. This study aims to describe mothers’ dietary patterns and dietary diversity and to identify characteristics associated with this dietary diversity. Methods: A cross sectional study was carried-out among 670 non-pregnant mothers […]

Invasive salmonellosis among children admitted to a Rural Tanzanian Hospital and a comparison with previous studies

Background: The importance of invasive salmonellosis in African children is well recognized but there is inadequate information on these infections. We conducted a fever surveillance study in a Tanzanian rural hospital to estimate the case fraction of invasive salmonellosis among pediatric admissions, examine associations with common co-morbidities and describe its clinical features. We compared our […]