Maternal mental health of adolescent mothers: a cross-sectional mixed-method study protocol to determine cultural and social factors and mental health needs in Lilongwe, Malawi

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Study Justification:
– Adolescence is a critical period of transition from childhood to adulthood, and becoming a mother during this time presents unique challenges that can have a significant impact on mental and physical health.
– There is limited research on how culture and social factors influence the mental health of adolescent mothers during the postpartum period in Malawi.
– Understanding these factors is crucial for developing appropriate interventions and support systems for adolescent mothers.
Study Highlights:
– The study will use a cross-sectional sequential mixed methods design, consisting of four phases: preparatory phase and scoping review, survey with adolescent mothers, qualitative study with health workers and informal healthcare providers, and development of recommendations for policy and practice.
– The study will investigate social and cultural influences on mental health among adolescent mothers in Lilongwe, Malawi, and examine the knowledge, attitudes, and practices of healthcare workers and informal healthcare providers.
– The findings will inform recommendations for policy, practice, prevention, and management interventions for adolescent mothers in Malawi.
Study Recommendations:
– The study aims to propose recommendations for an appropriate, culturally accepted spectrum of interventions, including universal, selective, and indicated prevention strategies.
– These recommendations will be based on the understanding of cultural and social factors that influence adolescent mothers’ mental health and well-being, as well as the identification of potential risk and protective factors.
Key Role Players:
– District Health Office
– Health facility staff
– Community volunteers
– Community representatives
– Adolescent mothers
– Parent representative
– Community health workers
– Feed the Children International (NGO working in Mitundu)
Cost Items for Planning Recommendations:
– Research personnel salaries
– Data collection materials (surveys, interview guides)
– Transcription and translation services
– Travel expenses for fieldwork
– Data analysis software
– Dissemination materials (conference presentations, publications)
– Ethical approval fees
Please note that the above cost items are examples and may not reflect the actual cost of the study.

The strength of evidence for this abstract is 7 out of 10.
The evidence in the abstract is rated 7 because it provides a clear description of the study design, objectives, and methods. However, it lacks specific details on the sample size, data collection procedures, and analysis methods. To improve the evidence, the abstract should include more information on these aspects, such as the planned sample size calculation, the interview and survey questions, and the planned statistical analyses.

INTRODUCTION: Adolescence marks a transition of life from childhood to adulthood. Becoming a mother during adolescence presents unique challenges that have a significant mental and physical burden and may increase the likelihood of developing common mental disorders (CMDs). Untreated CMDs have serious effects on both the mother and her child. Culture constitutes an important context for most experiences, and affects how individuals seek help. However, there is limited research that has investigated how culture and social factors influence the adolescent mother’s mental health during the postpartum period in Malawi. METHODS/DESIGN: A cross-sectional sequential mixed methods design will be carried out in four phases. Phase one will include the preparatory phase and scoping review. The second phase will comprise a survey with adolescent mothers. The sample for the survey consists of adolescent postpartum mothers aged 14-19 years (with infants of up to 6 months of age) who have the capacity to consent for the study. Phase three will be a qualitative study in which in-depth interviews and focus group discussions will be employed to collect data from health workers and informal healthcare providers in the community (eg, traditional healers, traditional birth attendants). The fourth phase will involve developing recommendations for policy and practice ETHICS AND DISSEMINATION: This study will provide an understanding of the impact of culture and social factors that influence adolescent mother’s mental health and well-being, including the identification of potential risk and protective factors. The findings will inform recommendations for an appropriate, culturally accepted spectrum of interventions, including universal, selective and indicated prevention strategies. The findings will be disseminated to stakeholders working in maternal health in Malawi. Ethical approval was received from the Curtin University Human Research Ethics Committee (HRE2021-0223) and (P.05/21/575) Malawian Ethics Board National Committee on Research Ethics in the Social Sciences and Humanities.

This mixed methods study aims to investigate social and cultural influences of mental health among adolescent mothers and their mental healthcare needs at Mitundu in Lilongwe District, Malawi. The study will also examine the community-based informal healthcare providers’ (traditional birth attendants, traditional healers, health volunteers, prophets, herbalists) and healthcare workers’ knowledge, attitudes and practices towards the mental health of adolescent mothers during the postpartum period. It will then propose recommendations for policy, practice, prevention and management interventions for adolescent mothers in Malawi. To address the aims of the study, the following objectives have been identified: The study will be guided by Bronfenbrenner’s (1994) bioecological model of human development that proposes individual health behaviour is a result of multiple levels of influence including intrapersonal (biological and psychological); interpersonal (social and cultural); and organisational (community, physical environment and policy) levels. The model provides a framework for understanding the broader context of cultural and social issues that may influence adolescent mental health.56 Although Bronfenbrenner’s model has not been applied specifically in the context of adolescent mothers previously, its applicability in specific mental health studies to address substance use and issues of safe schools makes it suitable for this purpose.57 58 A cross-sectional sequential model of mixed methods will be applied (see figure 1). The study will be conducted in four phases: (1) a scoping review of the literature and building public partnership with community representative, stakeholders and policy-makers for their involvement in informing the research; (2) an interview administered survey with adolescent mothers; (3) interviews and (focus group discussion (FGD)) with health workers and community informal healthcare providers; and (4) recommendations and dissemination. The study will commence in November 2021 until December 2024. Illustration of the proposed sequential model of mixed methods research and phases of study design implementation. The study will be conducted at Mitundu which is located in the rural area of Lilongwe district. The area is dominated by Chewa tribe which comprise 34% of all tribes in Malawi, has the largest population within the district and the highest rates of early marriages.8 Trends associated with education level, religion, ethnicity, wealth quintile, age distribution, fertility rates, as well as living conditions are similar in Mitundu when compared with other rural areas in Malawi.8 Mitundu has a population of 147 823 people, with 29 171 households and 402 villages. About 48% people are aged under 15 years. The district adolescent fertility rate of women between the ages of 14 and 19 years is 165 per 1000 women. This area is characterised by high levels of poverty, high rates of early marriages, malnutrition and 90% of the population are subsistence farmers.8 Twelve per cent of women have never attained any education and 62% have only completed primary school.8 The population’s expected number of pregnancies is 7391 per year.59 The only health facility in the area is Mitundu Rural Hospital (MRH) where there is an average of 135 deliveries at the by adolescent mothers each month.59 The scoping review will be conducted to inform the study design.60 61 In this study, the scoping review will focus on exploring the available evidence on current interventions that address CMDs among adolescent mothers in SSA. Both qualitative and quantitative evidence will be considered. The search will include peer reviewed journals from multidisciplinary and subject specific core electronic data bases such as Medline, EMBASE, Cumulative Index to Nursing and Allied Health Literature (CINAHL), PsychINFO, ProQuest, Google Scholar and grey literature sources from reputable health and welfare organisations, as well as scanning of reference lists of relevant studies (online supplemental file 1). The search strategy will be limited to English language with restrictions to studies published from year 2000. The identified studies will be organised and systematically integrated with the aim of establishing evidence on what is currently known about the contextual mental health interventions to address the mental health of adolescent during the perinatal period in Africa. A three-step method as recommended by Joanna Briggs Institute systematic reviews will be employed using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses.62 bmjopen-2021-056765supp001.pdf Partnerships with key stakeholders and organisations engaged in Maternal and Child Health services in the study area will be established. A steering committee will include key stakeholders from the District Health Office, health facility staff, community volunteers, community representatives, adolescent mothers, parent representative, community health workers and Feed the Children International (a Non-Governmental Organisation working in Mitundu) and will adopt an advisory role in all the stages of the study. A half-day briefing session will be conducted by the lead author to present the study concept to stakeholders. A survey including closed and open-ended questions will be developed and administered verbally to adolescent mothers (online supplemental file 2). Participants will be recruited via convenience sampling when they present for postnatal check-ups and under-5 clinics at the health facility and at care groups (community-based groups where perinatal women meet for nutrition and other health education session at the community level). To calculate the sample size for the study, Slovin sample size determination formula n=N/(1+N∗(e)2) will be used. In this study, N (30 653) is the population of adolescent mothers who are expected to deliver at Mitundu Hospital during one calendar year. The level of precision (e) is 5% at 95% CI. Substituting these values of parameters into the formula; n=30653/(1+30653∗0.0025), this provides a minimum study sample size of 395. bmjopen-2021-056765supp002.pdf Adolescent mothers aged 14–19 years and in their postpartum period (up to 6 months post delivery); able to understand the study information and to provide informed consent; and currently living at Mitundu area. The survey will include six sections. Demographics collected will include: household income, parity, tribe, occupation, education, marital status, financial support and perceived social support. Socioeconomic status will be measured by the Wealth Index.63 This tool was designed by the World Bank to measure the household socioeconomic status in low-income countries on the basis of household’s ownership of consumer goods, dwelling characteristics, type of drinking water source, toilet facilities and other characteristics.63 Household assets are combined into a composite index of economic status using principal component analysis.63 64 The tool has been validated and used in Malawi.8 63 65 Perceived social support will be assessed using the validated Multidimensional Scale of Perceived Social Support tool (MSPSS).61 The MSPSS has been evaluated for validity in Malawi, with the tool reporting high internal consistency for the full scale in Chichewa language.65 This section will collect information on alcohol consumption, tobacco smoking and experience of intimate partner violence. Alcohol use will be assessed using AUDIT-C. The tool assesses alcohol consumption by asking three questions focusing on the frequency and level of alcohol consumption.66 67 This tool is also validated for use in Chichewa language.68 Intimate partner violence will be assessed using the Hurt, Insulted, Threatened, Screamed at and Sexually Abused questionnaire.69 The Malawi Demographic Health Survey adapted questions for this tool to assess violence among married and pregnant women in Malawi.8 Participants will be screened for symptoms of anxiety using the Generalised Anxiety Disorder 7-item (GAD-7) scale. The GAD-7 has demonstrated an internal reliability of Cronbach alpha α=68 coefficient in Ghana and Cote d’Ivoire, and has been used in these countries to assess for anxiety in pregnant women. Studies conducted in Ghana found the threshold score ≥10 had a sensitivity of 89% and specificity of 80% for generalised anxiety.70 While there are no published studies using the GAD-7 among perinatal women in Malawi, it has been used to measure anxiety in a longitudinal study conducted to investigate mental health in mature adults with HIV.71 GAD-7 has been validated for use in high-income, middle-income and low-income countries.70 Research has supported the construct validity of the interviewer administered tool in local language.71 Depression will be assessed using the Edinburg Postnatal Depression Scale (EPDS). EPDS is a 10-item scale used for diagnosing symptoms of depression experienced in the past 7 days.21 It is widely used either as a population-based self-report or a health-worker administered measure.21 Studies in Malawi have found internal validity of the EPDS to be high and the tool demonstrates diagnostic accuracy, concurrent validity and reliability.21 72 The sensitivity index ranged from 68.8% to 100%; the specificity index 79.5 and reliability (Cronbach’s alpha) 0.9 (21, 72). There is evidence that mental health problems among adolescent mothers are a result of the SARS-CoV-2 (COVID-19) pandemic and associated restrictions.73 As data will be collected during the COVID-19 pandemic, open-ended questions around support and access to services will be included. In addition, participants will be asked questions around the influence of the pandemic and isolation measures on cultural practices and their general well-being. Open and closed-ended questions will be used to collect information about cultural practices in relation to mental health and mental illness. Questions will be adapted from a study conducted in Ghana exploring cultural factors related to pregnancy.37 Examples of items on the instrument are: being isolated in family activities because you have a baby; strict cultural rules, beliefs and practices regarding pregnancy and childbirth; being forced to get married; and religious support of sex before marriage.37 Open-ended questions will explore challenges during pregnancy, delivery and postpartum, their mental health needs and how they would like to be supported in addition to cultural practices around pregnancy. Participants will be recruited through information distributed at clinics, care groups and the MRH. A care group involves people from 8 to 12 households who meet regularly for peer education, counselling on nutrition and other health-related support. Interested adolescents meeting the eligibility criteria will be given an information sheet and consent form which will clearly outline the aim of the study, the procedures that will be involved, and the implications of participating in the study. The information sheet and consent form will be read to participants in Chichewa by the research assistant if required. The voluntary nature of the study will be emphasised. Ethical approval has been granted to apply mature minor status to the adolescent mothers. Participants who are illiterate and not able to sign their name will be requested to use their thumb print as a signature (this is standard practice in Malawi). Administration of the survey will be conducted at, or close to the clinic in a quiet and private area. The survey will take approximately 45 min and will be administered in Chichewa by a trained research assistant. Semistructured interviews will be conducted with healthcare workers (ie, nurses, clinical officers, community health workers) who will be recruited through snowballing sampling technique. In addition, FGDs with informal healthcare providers (two FDGs with health volunteers; two with church prophets and spiritual counsellors from church; and two with traditional healers, traditional birth attendants and herbalists) from within the catchment area of Mitundu. Participants will be purposively recruited and will include individuals who have the potential to provide rich, relevant and diverse information as they provide informal healthcare support to young mothers in the community. Data will be collected until data saturation is achieved; however, the numbers provided represent a guide.74 Participants will be over 18 years, able to consent and able to understand the study information. A semistructured interview guide will be used to guide the discussion during data collection for in-depth interviews and FGDs. Questions will be derived from the research objectives, literature review, theoretical framework and the survey findings. In-depth interviews with health workers will be facilitated in English (as their official workplace language); however, participants will be allowed the flexibility to respond in both English and Chichewa to allow full expression of concepts. FDGs with informal healthcare providers will be conducted in Chichewa as their English literacy is likely to be low. Interviews and FGDs will be audio recorded. Interview guides will be pretested with purposively selected participants (n=4) at another rural health facility and its surrounding community within the Lilongwe District with similar social demographic characteristics as Mitundu. Quantitative data will be analysed using SPSS software V.27. Descriptive statistics will be used to analyse the general characteristics of the study participants such as age, sex, educational level, socioeconomic status, number of children, and marital status, use of alcohol, gender-based violence, insight, support, history of mental illness, HIV status, and whether the pregnancy was planned or wanted. Means and SD will be calculated for overall scores and subgroups scores. Differences between categorical and continuous variables will be analysed by χ2 test and t-test, respectively. The differences in means of different groups will be analysed by t-test and analysis of variance. Multivariate statistics will be used to identify predictors of each common mental health disorder. Logistic regression will be used to identify association of factors to CMD. Statistical significance based on two-sided tests will be set at 0.05. The results of the regression models will be reported as ORs with 95% CIs. Qualitative data from in-depth interviews and FGDs will be transcribed verbatim and analysed using thematic analysis. NVivo V.10 will be used to manage and organise data. A three-phased coding of open, axial and selective data will be conducted75. Audio recordings of all interviews, transcripts and written notes obtained during an in-depth interview will be read and re-read by the lead author to facilitate familiarisation with the content, and discern overall sense and meaning and generate an initial list of ideas.76 The generated data will be rechecked line by line to acquire common phrases, key words, statements and patterns that may produce codes.76 The different codes will then be sorted into potential themes and collate them within the identified themes.76 The lead author will review the presumption to identify if the units of meaning reflect the research. Additionally, to ensure truthfulness, and authentic account, the lead author and two other two authors persons will examine the aspects of experience within the context of the entire experience to verify if the suggested meaning is probable.74 It is anticipated that the recommendations will inform policy and practice to enhance mental health outcome for adolescent mothers in Malawi. Results of the study will be presented at research conferences and peer reviewed publications. A copy of the results will be given to the Malawian Ethics Board National Committee on Research Ethics in the Social Sciences and Humanities, Ministry of Health and the facility where the study will be conducted. A presentation of results and study recommendations will be delivered to Ministry of Health Policy makers and other relevant stakeholders engaged in youth reproductive health services and maternal health in Malawi.

Based on the provided description, here are some potential innovations that could improve access to maternal health for adolescent mothers in Malawi:

1. Mobile Health (mHealth) Solutions: Develop mobile applications or text messaging services that provide adolescent mothers with information and support regarding maternal health, including prenatal care, postpartum care, and mental health resources.

2. Community-Based Interventions: Implement community-based programs that involve traditional birth attendants, traditional healers, and other informal healthcare providers in promoting maternal mental health. This could include training these providers on identifying and addressing mental health issues, as well as integrating mental health services into their existing practices.

3. Peer Support Groups: Establish peer support groups specifically for adolescent mothers, where they can share experiences, receive emotional support, and access information about maternal health. These groups can be facilitated by trained healthcare workers or community volunteers.

4. School-Based Interventions: Collaborate with schools to provide comprehensive sexual and reproductive health education, including information on maternal health, to adolescent girls. This can help prevent early pregnancies and ensure that young girls have the knowledge and resources to take care of their own health and well-being.

5. Task-Shifting: Train and empower community health workers to provide basic mental health support and counseling to adolescent mothers. This can help bridge the gap in mental health services and ensure that young mothers have access to the care they need.

6. Policy and Advocacy: Advocate for policy changes that prioritize maternal mental health and ensure that adolescent mothers have access to appropriate and culturally sensitive mental health services. This can include increasing funding for maternal health programs, improving healthcare infrastructure, and reducing stigma surrounding mental health.

These are just a few potential innovations that could be considered to improve access to maternal health for adolescent mothers in Malawi. It’s important to note that the specific recommendations should be based on the findings of the study and the needs identified within the local context.
AI Innovations Description
The study described aims to investigate the social and cultural factors that influence the mental health of adolescent mothers during the postpartum period in Lilongwe, Malawi. It also aims to identify the mental healthcare needs of these mothers and propose recommendations for policy, practice, prevention, and management interventions. The study will be conducted in four phases: a scoping review, a survey with adolescent mothers, qualitative interviews and focus group discussions with health workers and informal healthcare providers, and the development of recommendations. The study will use a mixed methods approach, combining quantitative and qualitative data collection and analysis. The findings of the study will be disseminated to stakeholders working in maternal health in Malawi and will inform the development of appropriate interventions to improve the mental health of adolescent mothers.
AI Innovations Methodology
Based on the provided description, here are some potential recommendations to improve access to maternal health for adolescent mothers in Malawi:

1. Increase awareness and education: Develop targeted educational programs to raise awareness about maternal mental health among adolescent mothers, their families, and the community. This can include information about the importance of mental health during the postpartum period, available support services, and strategies for coping with common mental disorders.

2. Strengthen community-based support: Enhance the role of community-based informal healthcare providers, such as traditional birth attendants and healers, in identifying and addressing mental health needs of adolescent mothers. This can involve training and capacity building programs to equip them with the knowledge and skills to provide appropriate support and referrals.

3. Improve access to healthcare services: Ensure that adolescent mothers have easy access to maternal healthcare services, including antenatal care, postnatal care, and mental health support. This can be achieved by increasing the number of healthcare facilities in rural areas, improving transportation options, and reducing financial barriers to accessing healthcare.

4. Promote culturally sensitive interventions: Develop interventions that are culturally appropriate and sensitive to the needs and beliefs of adolescent mothers in Malawi. This can involve integrating traditional practices and beliefs into mental health interventions, as well as involving community leaders and elders in the design and implementation of programs.

To simulate the impact of these recommendations on improving access to maternal health, a methodology could include the following steps:

1. Baseline data collection: Collect data on the current state of access to maternal health services and mental health outcomes among adolescent mothers in the study area. This can involve surveys, interviews, and focus group discussions with adolescent mothers, healthcare workers, and community members.

2. Development of a simulation model: Create a simulation model that represents the key factors and relationships influencing access to maternal health. This can be done using a combination of quantitative and qualitative data, as well as existing literature and expert knowledge. The model should capture the impact of the recommendations on various outcomes, such as healthcare utilization, mental health outcomes, and satisfaction with services.

3. Parameter estimation: Estimate the parameters of the simulation model based on the collected data and existing evidence. This may involve statistical analysis, expert opinion, and literature review to determine the effect sizes and probabilities associated with each recommendation.

4. Scenario testing: Simulate different scenarios by varying the implementation of the recommendations. This can involve changing the coverage, intensity, or timing of the interventions to assess their potential impact on access to maternal health. Compare the outcomes of each scenario to the baseline data to evaluate the effectiveness of the recommendations.

5. Sensitivity analysis: Conduct sensitivity analysis to assess the robustness of the results to changes in the model parameters. This can help identify the most influential factors and uncertainties in the simulation model.

6. Interpretation and reporting: Analyze the simulation results and interpret the findings in the context of the study objectives. Report the potential impact of the recommendations on improving access to maternal health, highlighting the key findings and implications for policy and practice.

It is important to note that the specific methodology for simulating the impact of the recommendations may vary depending on the available data, resources, and expertise. The above steps provide a general framework for conducting a simulation study in this context.

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