Cost effectiveness of medical devices to diagnose pre-eclampsia in low-resource settings

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Study Justification:
– Maternal mortality is a significant health challenge in developing countries, with pre-eclampsia being a major contributor.
– Diagnosis of pre-eclampsia requires appropriate medical devices and skilled health providers, which may be lacking in low-resource settings.
– This study aims to assess the cost-effectiveness of different medical devices used to diagnose pre-eclampsia in low- and middle-income countries (LMICs).
Highlights:
– The study conducted a cost-effectiveness analysis of various medical devices for diagnosing pre-eclampsia in LMICs.
– The results showed that the most cost-effective device combination was a semi-automatic blood pressure measurement device and visually read urine strip test.
– The combined per-use cost of this device combination was $0.2004, with an incremental cost effectiveness ratio of $93.6 per disability-adjusted life year (DALY) gained.
– The study found that improving access to treatment is more cost-effective than increasing testing rates or diagnostic device sensitivity when access to treatment is limited.
– Simple devices were found to be more cost-effective than complex devices.
– The study emphasized the importance of two design features for medical devices in LMICs: ease of use and accuracy without calibration.
Recommendations:
– Policy makers should prioritize improving access to treatment for pre-eclampsia in low-resource settings.
– Health economists should consider the cost-effectiveness of different medical devices when making decisions about resource allocation.
– Health care providers should focus on using simple and easy-to-use devices for diagnosing pre-eclampsia in LMICs.
– Engineers should design medical devices that are accurate without requiring calibration and are suitable for use in low-resource settings.
Key Role Players:
– Policy makers
– Health economists
– Health care providers
– Engineers
Cost Items for Planning Recommendations:
– Development and production of cost-effective medical devices
– Training and capacity building for health care providers
– Infrastructure improvements to support access to treatment
– Research and evaluation to monitor the effectiveness of interventions
– Advocacy and awareness campaigns to promote the importance of pre-eclampsia diagnosis and treatment

Background Maternal mortality remains a major health challenge facing developing countries, with pre-eclampsia accounting for up to 17% of maternal deaths. Diagnosis requires skilled health providers and devices that are appropriate for low-resource settings. This study presents the first cost-effectiveness analysis of multiple medical devices used to diagnose pre-eclampsia in low- and middle-income countries (LMICs). Methods Blood pressure and proteinuria measurement devices, identified from compendia for LMICs, were included. We developed a decision tree framework to assess the cost-effectiveness of each device using parameter values that reflect the general standard of care based on a survey of relevant literature and expert opinion. We examined the sensitivity of our results using one-way and second-order probabilistic multivariate analyses. Results Because the disability-adjusted life years (DALYs) averted for each device were very similar, the results were influenced by the per-use cost ranking. The most cost-effective device combination was a semi-automatic blood pressure measurement device and visually read urine strip test with the lowest combined per-use cost of $0.2004 and an incremental cost effectiveness ratio of $93.6 per DALY gained relative to a baseline with no access to diagnostic devices. When access to treatment is limited, it is more cost-effective to improve access to treatment than to increase testing rates or diagnostic device sensitivity. Conclusions Our findings were not sensitive to changes in device sensitivity, however they were sensitive to changes in the testing rate and treatment rate. Furthermore, our results suggest that simple devices are more cost-effective than complex devices. The results underscore the desirability of two design features for LMICs: ease of use and accuracy without calibration. Our findings have important implications for policy makers, health economists, health care providers and engineers.

The recommendation to improve access to maternal health in low-resource settings is to focus on the cost effectiveness of medical devices used to diagnose pre-eclampsia. This recommendation is based on a study published in Development Engineering in 2017.

Pre-eclampsia is a significant contributor to maternal mortality in developing countries, accounting for up to 17% of maternal deaths. However, diagnosing pre-eclampsia requires skilled health providers and appropriate devices that are suitable for low-resource settings.

The study conducted a cost-effectiveness analysis of various medical devices used to diagnose pre-eclampsia in low- and middle-income countries. The devices included blood pressure measurement devices and visually read urine strip tests, which were identified from compendia for low-resource settings.

Using a decision tree framework, the study assessed the cost-effectiveness of each device based on parameter values derived from a survey of relevant literature and expert opinion. The disability-adjusted life years (DALYs) averted for each device were found to be similar, with the results being influenced by the per-use cost ranking.

The most cost-effective combination of devices identified was a semi-automatic blood pressure measurement device and visually read urine strip test. This combination had the lowest combined per-use cost and an incremental cost effectiveness ratio compared to a baseline with no access to diagnostic devices.

The study also found that when access to treatment is limited, it is more cost-effective to improve access to treatment rather than increasing testing rates or diagnostic device sensitivity. Additionally, the study highlighted that simple devices are more cost-effective than complex devices.

The findings of this study have important implications for policy makers, health economists, health care providers, and engineers. The study emphasizes the importance of designing medical devices for low-resource settings that are easy to use and accurate without requiring calibration.

Overall, focusing on the cost effectiveness of medical devices to diagnose pre-eclampsia in low-resource settings can be a valuable innovation to improve access to maternal health.
AI Innovations Description
The recommendation to improve access to maternal health is to focus on the cost effectiveness of medical devices used to diagnose pre-eclampsia in low-resource settings. This recommendation is based on a study published in Development Engineering in 2017.

The study highlights that pre-eclampsia is a significant contributor to maternal mortality in developing countries, accounting for up to 17% of maternal deaths. However, diagnosing pre-eclampsia requires skilled health providers and appropriate devices that are suitable for low-resource settings.

The study conducted a cost-effectiveness analysis of various medical devices used to diagnose pre-eclampsia in low- and middle-income countries. The devices included blood pressure measurement devices and visually read urine strip tests, which were identified from compendia for low-resource settings.

Using a decision tree framework, the study assessed the cost-effectiveness of each device based on parameter values derived from a survey of relevant literature and expert opinion. The disability-adjusted life years (DALYs) averted for each device were found to be similar, with the results being influenced by the per-use cost ranking.

The most cost-effective combination of devices identified was a semi-automatic blood pressure measurement device and visually read urine strip test. This combination had the lowest combined per-use cost of $0.2004 and an incremental cost effectiveness ratio of $93.6 per DALY gained compared to a baseline with no access to diagnostic devices.

The study also found that when access to treatment is limited, it is more cost-effective to improve access to treatment rather than increasing testing rates or diagnostic device sensitivity. Additionally, the study highlighted that simple devices are more cost-effective than complex devices.

The findings of this study have important implications for policy makers, health economists, health care providers, and engineers. The study emphasizes the importance of designing medical devices for low-resource settings that are easy to use and accurate without requiring calibration.

Overall, focusing on the cost effectiveness of medical devices to diagnose pre-eclampsia in low-resource settings can be a valuable innovation to improve access to maternal health.
AI Innovations Methodology
To simulate the impact of the main recommendations of this abstract on improving access to maternal health, a methodology could be developed as follows:

1. Identify the target low-resource settings: Determine the specific countries or regions where access to maternal health is limited and pre-eclampsia is a significant contributor to maternal mortality.

2. Collect baseline data: Gather information on the current state of access to maternal health in the selected settings, including the prevalence of pre-eclampsia, availability of diagnostic devices, and access to treatment.

3. Define intervention parameters: Based on the study’s recommendations, establish the specific intervention parameters to be simulated, such as the introduction of the cost-effective combination of medical devices (semi-automatic blood pressure measurement device and visually read urine strip test) and improvements in access to treatment.

4. Develop a simulation model: Create a simulation model that incorporates the baseline data and intervention parameters. The model should consider factors such as population size, testing rates, treatment rates, device costs, and the impact of the recommended devices on diagnosis and subsequent treatment.

5. Run the simulation: Use the simulation model to simulate the impact of the recommended interventions on improving access to maternal health. This could involve running multiple scenarios with varying parameters to assess the potential outcomes.

6. Analyze the results: Evaluate the simulation results to determine the projected impact of the interventions on key indicators, such as reduction in maternal mortality, increase in access to diagnosis and treatment, and cost-effectiveness compared to the baseline scenario.

7. Interpret the findings: Interpret the simulation results to understand the potential benefits and limitations of implementing the recommended interventions. Consider the implications for policy makers, health economists, health care providers, and engineers in terms of resource allocation, implementation strategies, and potential challenges.

8. Communicate the findings: Present the findings of the simulation in a clear and concise manner to relevant stakeholders, including policy makers, health professionals, and researchers. Highlight the potential benefits of focusing on cost-effective medical devices to diagnose pre-eclampsia in low-resource settings and emphasize the importance of improving access to treatment.

By following this methodology, stakeholders can gain insights into the potential impact of implementing the recommendations from the study and make informed decisions regarding strategies to improve access to maternal health in low-resource settings.

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