Aim: Hypertension control in Sub-Saharan Africa (SSA) is the worst (less than one out of ten) when compared to the rest of the world. Therefore, this scoping review was conducted to identify and describe the possible reasons for poor blood pressure (BP) control based on 4Ps’ (patient, professional, primary healthcare system, and public health policy) factors. Methods: PRISMA extension for scoping review protocol was used. We systematically searched articles written in the English language from January 2000 to May 2020 from the following databases: PubMed/Medline, Embase, Scopus, Web of Science, and Google scholar. Results: Sixty-eight articles were included in this scoping review. The mean prevalence of hypertension, BP control, and patient adherence to prescribed medicines were 20.95%, 11.5%, and 60%, respectively. Only Kenya, Malawi, and Zambia out of ten countries started annual screening of the high-risk population for hypertension. Reasons for nonadherence to prescribed medicines were lack of awareness, lack of access to medicines and health services, professional inertia to intensify drugs, lack of knowledge on evidence-based guidelines, insufficient government commitment, and specific health behaviors related laws. Lack of screening for high-risk patients, non-treatment adherence, weak political commitment, poverty, maternal and child malnutrition were reasons for the worst BP control. Conclusion: In conclusion, the rate of BP treatment, control, and medication adherence was low in Eastern SSA. Screening for high-risk populations was inadequate. Therefore, it is crucial to improve government commitment, patient awareness, and access to medicines, design country-specific annual screening programs, and empower clinicians to follow individualized treatment and conduct medication adherence research using more robust tools.
In eastern SSA, there is lack of comprehensive evidence on reasons of poor blood pressure control. Out of 20 Eastern SSA countries, we included ten countries in this review. Countries included were; Ethiopia, Kenya, Malawi, Mozambique, Rwanda, Seychelles, United Republic of Tanzania, Uganda, Zambia, and Zimbabwe [19, 20]. Countries are selected based on the following criteria: availability of recent national STEPS survey report, availability of primary health system capacity survey to provide care for patients with CVDs, availability of national chronic disease management strategies, accessibility of national health policy, and accessibility of health sector improvement strategies, directives, strategies, guidelines, and manuals. We searched articles written in the English language from January 2000 to May 2020 from the following databases: PubMed/Medline, Embase, Scopus, Web of Science, and Google Scholar with a systematic search query (available in Additional file 1). The following national documents are included in addition to systematically searched articles. These include the National health policy of selected countries, national chronic disease prevention, management and control strategies of selected countries, national quality improvement strategies, and national technology integration strategies. Systematic reviews, clinical trials, cohort studies, observational and cross-sectional studies related to uncontrolled blood pressure and associated factors. Systematic reviews, clinical trials, cohort studies, observational and cross-sectional studies related to uncontrolled blood pressure and associated (patient, professional, public policy, and political) factors among adults in Eastern Sub-Saharan Africa are included. Studies conducted before January 2000, short communications, and conference proceedings are excluded. Articles that are not related to uncontrolled blood pressure and associated (patient, professional, public policy and political) factors among adults in Eastern Sub-Saharan Africa are excluded. From a total of 421 articles identified by the literature search, 172 potentially relevant articles were abstracted. After applying the inclusion–exclusion criteria listed above, 68 articles were found to be relevant (Fig. 1). Two investigators independently reviewed each study’s abstract against pre-specified inclusion and exclusion criteria. In case of disagreement on the article’s quality, two authors discussed In front of the table in the third and fourth authors’ presence. Flowchart representing the selection of sources of evidence and the number of articles excluded and eligible for review Two investigators abstracted population CVD risk factors, level of uncontrolled blood pressure, 4Ps (patient, professional, primary healthcare, and public policy related factors) associated with uncontrolled blood pressure data from all included studies. A second investigator checked these data for accuracy. Disagreements among us are managed through discussion in the presence of other authors. Prevalence of blood pressure control, patient-related, professional-related, primary healthcare system-related, and public health policy and politics, determinants of poor blood pressure control are used as data-items. We qualitatively described and summarized the evidence on blood pressure control based on 4P’s (primary care, patient, professional, and public health policy-related factors). We also described the major primary healthcare challenges contributing to the region’s worst BP control and strategies to address them.