Treatment gap and help-seeking for postpartum depression in a rural African setting

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Study Justification:
– Postpartum depression (PPD) affects more than one in ten women and has adverse consequences for mother, child, and family.
– Integrating mental health care into maternal health care platforms can improve access to effective care and reduce the treatment gap in low- and middle-income countries.
Study Highlights:
– Only 4.2% of women with high PPD symptoms sought mental health care, and only 12.7% had been in contact with any health service since the onset of their symptoms.
– Factors associated with help-seeking from health services included urban residence, strong social support, perceived physical cause, perceived higher severity, perceived need for treatment, PHQ score, and disability.
– More than half of the women with high levels of PPD symptoms attributed their symptoms to a psychosocial cause, and equal proportions endorsed biomedical treatment and traditional or religious healing as appropriate interventions.
Study Recommendations:
– Create public awareness about PPD, its causes and consequences, and the need for help-seeking.
– Integrate mental health care into maternal health care services within primary care to address the treatment gap.
Key Role Players:
– Mental health professionals
– General health workers
– Community-based health extension workers
– Traditional and faith healers
– Parents, friends, partners, and relatives for informal support
Cost Items for Planning Recommendations:
– Training and capacity building for health care personnel
– Public awareness campaigns
– Integration of mental health care into existing maternal health care services
– Infrastructure improvements for mental health care services
– Monitoring and evaluation of interventions

The strength of evidence for this abstract is 7 out of 10.
The evidence in the abstract is moderately strong, but there are some areas for improvement. The study design is a population-based cross-sectional survey, which provides a good foundation for gathering data. The sample size of 3147 women is relatively large, which increases the reliability of the findings. The use of a culturally validated version of the Patient Health Questionnaire (PHQ-9) to screen for depressive symptoms adds to the validity of the study. The multiple logistic regression analysis helps identify factors associated with help-seeking from health services. However, there are some limitations to consider. The study was conducted in a specific rural African setting, which may limit the generalizability of the findings to other contexts. The study relies on self-report measures, which may introduce bias. Additionally, the study does not provide information on the response rate or any potential non-response bias. To improve the strength of the evidence, future studies could consider using a longitudinal design to assess changes in help-seeking behavior over time. It would also be beneficial to include a control group for comparison. Finally, conducting the study in multiple settings and diverse populations would enhance the generalizability of the findings.

Background: Postpartum depression (PPD) affects more than one in ten women and is associated with adverse consequences for mother, child and family. Integrating mental health care into maternal health care platforms is proposed as a means of improving access to effective care and reducing the ‘treatment gap’ in low- and middle-income countries. This study aimed to determine the proportion of women with PPD who sought help form a health facility and the associated factors. Methods: A community based, cross-sectional survey was conducted in southern Ethiopia. A total of 3147 women who were between one and 12 months postpartum were screened for depressive symptoms in their home using a culturally validated version of the Patient Health Questionnaire (PHQ-9). Women scoring five or more (indicating potential depressive disorder) (n = 385) were interviewed regarding help-seeking behavior. Multiple logistic regression was used to identify factors associated independently with help-seeking from health services. Results: Only 4.2 % of women (n = 16) with high PPD symptoms had obtained mental health care and only 12.7 % of women (n = 49) had been in contact with any health service since the onset of their symptoms. In the multivariable analysis, urban residence, adjusted odds ratio (aOR): 4.39 (95 % confidence interval (CI) 1.23, 15.68); strong social support, aOR: 2.44 (95 % CI 1.30, 4.56); perceived physical cause, aOR: 6.61 (95 % CI 1.76, 24.80); perceived higher severity aOR: 2.28 (95 % CI 1.41, 5.47); perceived need for treatment aOR: 1.46 (95 % CI 1.57, 18.99); PHQ score, aOR: 1.14 (95 % CI 1.04, 1.25); and disability, aOR: 1.06 (95 % CI 1.01, 1.15) were associated significantly with help-seeking from health services. More than half of the women with high levels of PPD symptoms (n = 231; 60.0 %) attributed their symptoms to a psychosocial cause and 269 (69.9 %) perceived a need for treatment. Equal proportions endorsed biomedical treatment and traditional or religious healing as the appropriate intervention. Conclusion: In the absence of an accessible maternal mental health service the treatment gap was very high. There is a need to create public awareness about PPD, its causes and consequences, and the need for help seeking. However, symptom attributions and help-seeking preferences indicate potential acceptability of interventions located in maternal health care services within primary care.

Study design: a population-based cross-sectional survey. Study area: the study was carried out in Sodo district, Gurage Zone, Southern Nations, Nationalities and Peoples Region (SNNPR) of Ethiopia. Sodo is located about 100 km south of the capital city, Addis Ababa. In the most recent census, the population was estimated to be 161,952 persons (79,356 men; 82,596 women), with 88 % of the population residing in rural areas [26]. Amharic is the official language in the district, but the second language for the majority of inhabitants. Within Sodo district, there are eight primary care health centers, each linked to health posts which are staffed by community-based health extension workers. The nearest psychiatric out-patient service is located in Butajira town, 30 km away from the capital of the Sodo district. At the time of the study there were no specialist mental health professionals located within the district and no health care personnel trained in mental health care. However, as part of the Program for Improving Mental health carE (PRIME), plans were being made to integrate mental health care into primary care and maternal health care settings across the district [27]. PRIME is a multi-country project involving five LMICs (Ethiopia, India, Nepal, South Africa and Uganda). PRIME aims to generate evidence on the best approaches for the integration of mental health care into the existing primary and maternal health care services. This study was conducted to inform possible models of intervention for maternal mental health care within the PRIME service model. As part of PRIME, a census of all households in the district was conducted. However, only 1427 infants (aged less than one year) were recorded within the census, a figure which was much lower than the estimated population from the Central Statistics Agency [28]. Second, we used the immunization report for under one year children from the district health office. Third, we checked the registry of pregnant and postpartum women which is compiled and maintained by community-based health extension workers. Finally, the data collectors identified eligible women in a house-to-house search. These combined approaches resulted in the identification of 3147 women between one and 12 months postpartum. All the identified women were screened using the Patient Health Questionnaire, 9-item depression scale (PHQ-9) [29] and women scoring five or more on the PHQ-9 formed the sample for the study presented in this paper. Postpartum depressive symptoms were measured using the PHQ-9. The PHQ-9 was developed originally to measure depression in primary care settings [30]. The PHQ-9 has been culturally validated for use in several African country settings [31–35] including in postpartum women in rural Ghana [36] and in the primary health care context in rural Ethiopia [37]. In the latter Ethiopian study of the criterion validity of the PHQ-9, a score of five or more was found to have a sensitivity of 83 % and specificity of 75 % for the detection of major depressive disorder. This was assessed using the General Help Seeking Questionnaire (GHSQ) [38]. The GHSQ is a 9-item instrument that was developed to assess future intentions to seek help from a list of culturally-relevant sources. We adapted the GHSQ to ask about actual (rather than intended) behavior and collapsed the response categories to yes/no. The sources of help included in the GHSQ are classified into two major classes: formal and informal. Formal help-seeking includes visiting health professionals (e.g., psychiatrists, psychologists, general practitioners, nurses, etc) or traditional and faith healers [38]. In a rural Ethiopian context, this was adapted to be ‘general health worker’ or ‘mental health worker’. Informal help-seeking is defined as talking about one’s symptoms with parents, friends, a partner or other relative. The woman’s explanatory model of postpartum depressive symptoms was investigated using the Short Explanatory Model Interview (SEMI) [39]. The SEMI is a semi-structured questionnaire with open ended questions to be documented verbatim and coded using a contextualized set of possible categories. A version of SEMI was adapted for Ethiopia with an expert consensus meeting involving mental health professionals and qualitative researchers with experience working in the study site. The women’s perceptions of causes, severity, treatment needs and options for symptoms of postpartum depression were assessed. Disability was measured using the World Health Organization Disability Assessment Tool (WHODAS) [40] which covers the functional domains of understanding and communicating, getting around, self-care, getting along with people, life activities, and participation in society. Each item was scored from 1 (none) to 5 (extreme or cannot do), with the total WHODAS score ranging from 36 to 180. The WHODAS has been used in Ethiopia in perinatal women in the neighboring district and found to have convergent validity and acceptability [41]. Social support was measured using the Oslo Social Support Scale (OSSS-3) [42] The OSSS-3 total score ranges between three and 14. Scores from 3 to 8 are considered to indicate poor support, scores from 9 to 11 indicate intermediate support, and a score between 12 and 14 is considered to indicate strong social support. Although these cut-off points have not been validated in the Ethiopian context, the OSSS-3 categories were used in a community study in the same Ethiopian district and showed good utility [43]. The Barriers to Access to Care Evaluation (BACE) was adapted for use in the study site [44]. Twenty-three out of 30 original items were used in this study as some of the items were not applicable for women with PPD living in a rural African context. For example items like “Concern that it might harm my chances when applying for jobs” and “Not wanting a mental health problem to be on my medical records” were excluded. The tool asks about a range of issues that have ever stopped, delayed or discouraged an individual from getting, or continuing with, professional care for a mental health problem on a scale from 0 (not at all) to 3 (a lot). The domains of potential barriers include individual perception (including stigma), infrastructure, knowledge, social support, attitude of respondents towards the available treatment and previous experiences. Women were interviewed in their homes privately by 36 trained data collectors who were trained for 9 days. The data collectors were recruited from the district and the sub-districts or, if no eligible person was available, applicants from the neighboring sub-districts were recruited. The educational levels of the data collectors ranged from tenth grade completed to first degree. They were supervised by four supervisors who were also trained and assisted by the investigators. The supervisors were diploma or degree graduates. The data collectors went house-to-house, explained the purpose of the research and either gave an information sheet to the woman or read the information for those who were unable to read. Women who consented to participate were interviewed at a time convenient for them within a day or two of initial contact. A pre-test was conducted in three sub-districts near the study area. Data were collected between April and June 2014. Data were double entered into EpiData version 3.1 and exported to SPSS-20 for analysis. Frequencies, percentages, and mean values were used to describe the categorical and continuous variables. Bivariate analyses were carried out to investigate the association between help-seeking behavior of women with symptoms of PPD from a general health facility and each of the independent variables. This outcome was of interest because of the plan to integrate mental health care for women into general health services. All variables with a p-value <0.2 were included in the multivariable model. Adjusted odds ratios with associated 95 % confidence intervals were reported in the final multiple logistic regression model.

The recommendation from the study is to integrate mental health care into maternal health care platforms in order to improve access to maternal health and reduce the treatment gap for postpartum depression (PPD) in low- and middle-income countries. This can be achieved by creating public awareness about PPD and the importance of seeking help, as well as providing training to health care providers in mental health care within primary care and maternal health care settings.

Some innovations that can be implemented based on these recommendations include:

1. Integrating mental health care services into existing maternal health care platforms: This involves incorporating mental health screening, assessment, and treatment services into routine maternal health care visits. This can help identify and address PPD symptoms early on and ensure that women receive the necessary care and support.

2. Public awareness campaigns: These campaigns can be conducted through various channels such as community meetings, radio broadcasts, and social media platforms. The aim is to educate the public about PPD, its causes, consequences, and the importance of seeking help. By reducing stigma and increasing knowledge about PPD, more women may be encouraged to seek help when needed.

3. Training and support for health care providers: Health care providers in primary care and maternal health care settings should receive training on identifying and managing PPD. This can include training on screening tools, counseling techniques, and referral pathways. Ongoing support and supervision should also be provided to ensure that health care providers feel confident and competent in addressing PPD.

4. Collaboration and coordination between different sectors: To effectively integrate mental health care into maternal health care platforms, collaboration and coordination between different sectors is crucial. This includes collaboration between mental health professionals, maternal health care providers, community health workers, and other stakeholders. By working together, these sectors can ensure a comprehensive and integrated approach to maternal mental health care.

Overall, the key innovations to improve access to maternal health and reduce the treatment gap for PPD include integrating mental health care into maternal health care services, raising public awareness about PPD, providing training to health care providers, and promoting collaboration and coordination between different sectors.
AI Innovations Description
The recommendation to improve access to maternal health in this study is to integrate mental health care into maternal health care platforms. This can help reduce the “treatment gap” for postpartum depression (PPD) in low- and middle-income countries. The study found that only a small proportion of women with high PPD symptoms sought help from a health facility. By integrating mental health care into maternal health care services, more women with PPD can receive the necessary care and support.

The study suggests creating public awareness about PPD, its causes, consequences, and the importance of seeking help. This can help reduce stigma and encourage women to seek help when needed. Additionally, the study highlights the need for trained health care personnel in mental health care within primary care and maternal health care settings. By providing training and support to health care providers, they can effectively identify and manage PPD.

Overall, the recommendation is to integrate mental health care into maternal health care services, raise awareness about PPD, and provide training to health care providers. This can help improve access to maternal health and reduce the treatment gap for PPD.
AI Innovations Methodology
To simulate the impact of the main recommendations on improving access to maternal health, a possible methodology could include the following steps:

1. Baseline Assessment: Conduct a survey or data collection to establish the current level of access to maternal health care and the prevalence of postpartum depression (PPD) in the target population. This could involve screening women for depressive symptoms using a culturally validated tool like the Patient Health Questionnaire (PHQ-9).

2. Intervention Implementation: Integrate mental health care into maternal health care platforms by training health care providers in identifying and managing PPD. This could involve providing training sessions and resources on PPD screening, diagnosis, and treatment within primary care and maternal health care settings. Additionally, create public awareness campaigns about PPD, its causes, consequences, and the importance of seeking help.

3. Post-Intervention Assessment: After implementing the intervention, conduct a follow-up survey or data collection to assess the impact on access to maternal health care. This could involve screening women for depressive symptoms again using the PHQ-9 and assessing their help-seeking behavior.

4. Data Analysis: Analyze the data collected before and after the intervention to determine the changes in access to maternal health care and help-seeking behavior. This could involve comparing the proportion of women seeking help from health facilities before and after the intervention, as well as identifying factors associated with help-seeking behavior using logistic regression analysis.

5. Evaluation: Evaluate the impact of the intervention by comparing the results of the post-intervention assessment with the baseline assessment. This could involve calculating the treatment gap reduction, changes in help-seeking behavior, and improvements in access to maternal health care.

By following this methodology, researchers can assess the effectiveness of integrating mental health care into maternal health care platforms and raising awareness about PPD in improving access to maternal health. The results can inform future interventions and policies aimed at reducing the treatment gap for PPD in low- and middle-income countries.

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